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Cellosaurus AG12797 (CVCL_X769)

[Text version]
Cell line name AG12797
Synonyms AG12797A
Accession CVCL_X769
Resource Identification Initiative To cite this cell line use: AG12797 (RRID:CVCL_X769)
Comments Population: Japanese.
Omics: miRNA expression profiling.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Thigh, skin; UBERON=UBERON_0004262.
Cell type: Fibroblast of skin; CL=CL_0002620.
Disease Werner syndrome (NCIt: C3447)
Werner syndrome (ORDO: Orphanet_902)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_EQ42 (iWS797)
Originate from same individual CVCL_X768 ! AG05233
CVCL_X770 ! AG12798
Sex of cell Male
Age at sampling 36Y
Category Finite cell line
Publications

CLPUB00597
National Institute on Aging
1994 catalog of cell lines. NIA Aging Cell Repository.
(In) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda (1994)

PubMed=10615119; DOI=10.1038/71630
Wyllie F.S., Jones C.J., Skinner J.W., Haughton M.F., Wallis C., Wynford-Thomas D., Faragher R.G.A., Kipling D.
Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts.
Nat. Genet. 24:16-17(2000)

PubMed=19966276; DOI=10.1093/nar/gkp1103
Johnson J.E., Cao K., Ryvkin P., Wang L.-S., Johnson F.B.
Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential.
Nucleic Acids Res. 38:1114-1122(2010)

PubMed=24749076; DOI=10.1016/j.stemcr.2014.02.006
Cheung H.-H., Liu X.-Z., Canterel-Thouennon L., Li L., Edmonson C., Rennert O.M.
Telomerase protects Werner syndrome lineage-specific stem cells from premature aging.
Stem Cell Reports 2:534-546(2014)

Cross-references
Cell line collections (Providers) Coriell; AG12797
Cell line databases/resources CLO; CLO_0022892
Encyclopedic resources Wikidata; Q54744468
Gene expression databases GEO; GSM476012
GEO; GSM1184272
GEO; GSM1184273
GEO; GSM1535461
GEO; GSM1535471
Entry history
Entry creation05-Sep-2014
Last entry update29-Jun-2023
Version number13