• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg290His (c.869G>A); ClinVar=VCV000127825; Zygosity=Unspecified (PubMed=11139287; PubMed=15863265).
  
• Mutation; HGNC; HGNC:12687; VHL; Simple; p.Leu178Glnfs (c.532_533insC); Zygosity=Unspecified (PubMed=10925357).
  

PubMed=9146668; DOI=10.1016/S0022-5347(01)64778-5
Uwe Ramp, Kai Jaquet, Petra Reinecke, Cordula Schardt, Ulrike Friebe-Hoffmann, Thorsten Nitsch, Nikolaus Marx, Helmut Erich Gabbert, Claus-Dieter Gerharz;
Functional intactness of stimulatory and inhibitory autocrine loops in human renal carcinoma cell lines of the clear cell type.
J. Urol. 157:2345-2350(1997)

PubMed=10925357; DOI=10.1002/1097-0215(20000901)87:5<650::AID-IJC5>3.0.CO;2-3
Alexander J. Meyer, Ana Hernandez, Andrea R. Florl, Jurgen Enczmann, Claus-Dieter Gerharz, Wolfgang Arthur Schulz, Peter Wernet, Rolf Ackermann;
Novel mutations of the von Hippel-Lindau tumor-suppressor gene and rare DNA hypermethylation in renal-cell carcinoma cell lines of the clear-cell type.
Int. J. Cancer 87:650-653(2000)

PubMed=11139287; DOI=10.1038/sj.cdd.4400746
Marion Dejosez, Uwe Ramp, Csaba Mahotka, Andreas Krieg, Henning Walczak, Helmut Erich Gabbert, Claus-Dieter Gerharz;
Sensitivity to TRAIL/APO-2L-mediated apoptosis in human renal cell carcinomas and its enhancement by topotecan.
Cell Death Differ. 7:1127-1136(2000)

CLPUB00407
Andreas Krieg;
Characterization and functional analysis of the TRAIL system and the inhibitor of apoptosis protein (IAP) family in human neoplasia.
Thesis MD (2005); Heinrich-Heine-Universitat Dusseldorf; Dusseldorf; Germany

PubMed=15863265; DOI=10.1016/j.canlet.2004.09.045
Petra Reinecke, Thomas Kalinski, Csaba Mahotka, Michael Schmitz, Marion Dejosez, Helmut Erich Gabbert, Claus-Dieter Gerharz;
Paclitaxel/taxol sensitivity in human renal cell carcinoma is not determined by the p53 status.
Cancer Lett. 222:165-171(2005)