Cellosaurus cell line HBEC5-KT (CVCL

Cellosaurus HBEC5-KT (CVCL_X493)

Cross-references
Cell line name	HBEC5-KT
Synonyms	HBEC5 KT; HBEC5KT; HBEC5
Accession	CVCL_X493
Resource Identification Initiative	To cite this cell line use: HBEC5-KT (RRID:CVCL_X493)
Comments	Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT. Genetic integration: Method=Transduction; Gene=MGI; MGI:88357; Cdk4. Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Omics: Transcriptomics; Microarray. Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031. Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	Age unspecified
Category	Telomerase immortalized cell line
Publications	PubMed=15604268; DOI=10.1158/0008-5472.CAN-04-3703 Ruben D. Ramirez, Shelley Sheridan, Luc Girard, Mitsuo Sato, Young Kim, Jon Pollack, Michael Peyton, Ying Zou, Jonathan M. Kurie, J. Michael DiMaio, Sara Milchgrub ...Show all 21 authors... , Alice L. Smith, Rhonda F. Souza, Laura Gilbey, Xi Zhang, Kenia G. Gandia, Melville B. Vaughan, Woodring Erik Wright, Adi F. Gazdar, Jerry W. Shay, John D. Minna; Show fewer authors Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins. Cancer Res. 64:9027-9034(2004)
Encyclopedic resources	Wikidata; Q54881418
Gene expression databases	GEO; GSM171897 GEO; GSM253434 GEO; GSM794411
Entry history
Entry creation	05-Sep-2014
Last entry update	14-Aug-2025
Version number	20