Cellosaurus cell line NT-1 [Human leukemia] (CVCL

Cross-references
Cell line name	NT-1 [Human leukemia]
Accession	CVCL_X338
Resource Identification Initiative	To cite this cell line use: NT-1 [Human leukemia] (RRID:CVCL_X338)
Comments	Population: Chinese. Doubling time: ~72 hours (PubMed=25012564). Caution: According to PubMed=25012564 the TP53 mutation is p.Pro215Arg; which does not correspond to the DNA sequence shown in figure 3. Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro278Ala (c.832C>G); ClinVar=VCV000376645; Zygosity=Unspecified (PubMed=25012564).
Disease	Atypical chronic myeloid leukemia, BCR-ABL1 negative (NCIt: C3519) Atypical chronic myeloid leukemia (ORDO: Orphanet_98824)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	67Y
Category	Cancer cell line
Publications	PubMed=25012564; DOI=10.1016/j.leukres.2014.06.008 Juan Qian, Qin-Rong Wang, Jie Liu, Sheng-Hua Jiang, Xiao-Qing Ni, Zeng-Hua Lin, Ya-Ping Zhang, Hong Liu; Establishment and characterization of a rare atypical chronic myeloid leukemia cell line NT-1. Leuk. Res. 38:1111-1116(2014)
Cell line databases/resources	cancercelllines; CVCL_X338
Encyclopedic resources	Wikidata; Q54931070
Entry history
Entry creation	17-Jul-2014
Last entry update	19-Dec-2024
Version number	14