Cellosaurus cell line SCCNC5 (CVCL

Cellosaurus SCCNC5 (CVCL_X159)

Cross-references
Cell line name	SCCNC5
Accession	CVCL_X159
Resource Identification Initiative	To cite this cell line use: SCCNC5 (RRID:CVCL_X159)
Comments	Omics: Variations; Array-based CGH. Derived from site: In situ; Nose, nasal cavity, maxillary sinus; UBERON=UBERON_0001764.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu171Lys (c.511G>A); ClinVar=VCV000141566; Zygosity=Unspecified (PubMed=24816148).
Disease	Sinonasal squamous cell carcinoma (NCIt: C68611) Squamous cell carcinoma of the nasal cavity and paranasal sinuses (ORDO: Orphanet_500464)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	79Y
Category	Cancer cell line
Publications	PubMed=24662767; DOI=10.1038/jid.2014.154; PMCID=PMC4753672 Andrew P. South, Karin J. Purdie, Stephen A. Watt, Sam Haldenby, Nicoline Y. den Breems, Michelle Dimon, Sarah T. Arron, Michael J. Kluk, Jon Christopher Aster, Angela McHugh, Dylan J. Xue ...Show all 17 authors... , Jasbani H.S. Dayal, Kim S. Robinson, S.M. Hasan Rizvi, Charlotte Mary Proby, Catherine A. Harwood, Irene May Leigh; Show fewer authors NOTCH1 mutations occur early during cutaneous squamous cell carcinogenesis. J. Invest. Dermatol. 134:2630-2638(2014) PubMed=24816148; DOI=10.1038/srep04925; PMCID=PMC4017217 Cristina Garcia-Inclan, Alejandro Lopez-Hernandez, Marta Alonso-Guervos, Eva Allonca, Sira Potes, Santiago Melon, Fernando Lopez, Jose Luis Llorente, Mario A.J.A. Hermsen; Establishment and genetic characterization of six unique tumor cell lines as preclinical models for sinonasal squamous cell carcinoma. Sci. Rep. 4:4925.1-4925.12(2014)
Cell line databases/resources	cancercelllines; CVCL_X159
Encyclopedic resources	Wikidata; Q54952389
Gene expression databases	GEO; GSM1377039
Polymorphism and mutation databases	Cosmic; 2614476
Entry history
Entry creation	17-Jul-2014
Last entry update	10-Apr-2025
Version number	16