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Cellosaurus H69/Txl (CVCL_X029)

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Cell line name H69/Txl
Accession CVCL_X029
Resource Identification Initiative To cite this cell line use: H69/Txl (RRID:CVCL_X029)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_45863; Paclitaxel (Taxol).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Gly106_Arg108del (c.317_325delGGCAACCGT); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9884; RB1; Simple; p.Glu748Ter (c.2242G>T); ClinVar=VCV000013078; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu171Ter (c.511G>T); ClinVar=VCV000634771; Zygosity=Homozygous (from parent cell line).
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1579 (NCI-H69)
Sex of cell Male
Age at sampling 55Y
Category Cancer cell line
Publications

PubMed=7514586; DOI=10.1111/j.1349-7006.1994.tb02096.x; PMCID=PMC5919448
Sei Ohta, Kazuto Nishio, Naohiro Kubota, Tohru Ohmori, Yasunori Funayama, Tatsuo Ohira, Hiroaki Nakajima, Mitsuru Adachi, Nagahiro Saijo;
Characterization of a taxol-resistant human small-cell lung cancer cell line.
Jpn. J. Cancer Res. 85:290-297(1994)

Cross-references
Cell line databases/resources cancercelllines; CVCL_X029
Encyclopedic resources Wikidata; Q54872202
Entry history
Entry creation17-Jul-2014
Last entry update19-Dec-2024
Version number17