| Cell line name |
hTERT-EEC-B37 |
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| Synonyms |
hTERT-EEC |
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| Accession |
CVCL_X007 |
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| Resource Identification Initiative |
To cite this cell line use: hTERT-EEC-B37 (RRID:CVCL_X007) |
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| Comments |
Problematic cell line: Contaminated. Shown to be a MCF-7 derivative (PubMed=22710073).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00462.
Population: Caucasian.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175. |
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| Sequence variations |
- Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
|
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| Disease |
Invasive breast carcinoma of no special type (NCIt: C4194) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_0031 (MCF-7) |
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| Sex of cell |
Female |
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| Age at sampling |
69Y |
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| Category |
Cancer cell line |
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| Web pages |
Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx |
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| Publications | PubMed=15821114; DOI=10.1677/jme.1.01550
Sabine Hombach-Klonisch, Astrid Kehlen, Paul A. Fowler, Berthold Huppertz, Frank K. Jugert, Gerlinde Bischoff, Elisabeth Schluter, Jorg Buchmann, Thomas Klonisch;
Regulation of functional steroid receptors and ligand-induced responses in telomerase-immortalized human endometrial epithelial cells.
J. Mol. Endocrinol. 34:517-534(2005) PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017; PMCID=PMC3432677
Christopher T. Korch, Monique A. Spillman, Twila A. Jackson, Britta M. Jacobsen, Susan K. Murphy, Bruce Arthur Lessey, Virgil Craig Jordan, Andrew Peter Bradford;
DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination.
Gynecol. Oncol. 127:241-248(2012) DOI=10.1530/jme.1.01550e
Sabine Hombach-Klonisch, Astrid Kehlen, Paul A. Fowler, Berthold Huppertz, Frank K. Jugert, Gerlinde Bischoff, Elisabeth Schluter, Jorg Buchmann, Thomas Klonisch;
Erratum to: Regulation of functional steroid receptors and ligand-induced responses in telomerase-immortalized human endometrial epithelial cells.
J. Mol. Endocrinol. 51:X1-X1(2013) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_X007
|
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| Biological sample resources |
BioSample; SAMN03151839
|
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| Encyclopedic resources |
Wikidata; Q54896620
|
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| Entry history |
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| Entry creation | 17-Jul-2014 |
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| Last entry update | 10-Apr-2025 |
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| Version number | 23 |
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