Cellosaurus cell line BEAS-2B/CYP2A6 (CVCL

Cellosaurus BEAS-2B/CYP2A6 (CVCL_WZ49)

Cross-references
Cell line name	BEAS-2B/CYP2A6
Synonyms	B-2A6
Accession	CVCL_WZ49
Resource Identification Initiative	To cite this cell line use: BEAS-2B/CYP2A6 (RRID:CVCL_WZ49)
Comments	Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:2610; CYP2A6. Transformant: Ad12-SV40 hybrid virus. Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031. Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0168 (BEAS-2B)
Sex of cell	Male
Age at sampling	Age unspecified
Category	Transformed cell line
Publications	PubMed=22743290; DOI=10.1016/j.tox.2012.06.010 Xue-Jiao Yang, Hui-Yuan Lu, Zi-Yin Li, Qian Bian, Liang-Lin Qiu, Zhong Li, Qi-Zhan Liu, Jian-Min Li, Xin-Ru Wang, Shou-Lin Wang; Cytochrome P450 2A13 mediates aflatoxin B1-induced cytotoxicity and apoptosis in human bronchial epithelial cells. Toxicology 300:138-148(2012) PubMed=23602888; DOI=10.1016/j.taap.2013.04.005 Xue-Jiao Yang, Zhan Zhang, Xi-Chen Wang, Yun Wang, Xiao-Ming Zhang, Hui-Yuan Lu, Shou-Lin Wang; Cytochrome P450 2A13 enhances the sensitivity of human bronchial epithelial cells to aflatoxin B1-induced DNA damage. Toxicol. Appl. Pharmacol. 270:114-121(2013) PubMed=24114584; DOI=10.1002/ijc.28489 Zhan Zhang, Hui-Yuan Lu, Fei Huan, Cromie Meghan, Xue-Jiao Yang, Yun Wang, Xi-Chen Wang, Xin-Ru Wang, Shou-Lin Wang; Cytochrome P450 2A13 mediates the neoplastic transformation of human bronchial epithelial cells at a low concentration of aflatoxin B1. Int. J. Cancer 134:1539-1548(2014)
Encyclopedic resources	Wikidata; Q93425310
Entry history
Entry creation	06-Sep-2019
Last entry update	10-Apr-2025
Version number	10