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Cellosaurus BEAS-2B/CYP2A13 (CVCL_WZ48)

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Cell line name BEAS-2B/CYP2A13
Synonyms B-2A13
Accession CVCL_WZ48
Resource Identification Initiative To cite this cell line use: BEAS-2B/CYP2A13 (RRID:CVCL_WZ48)
Comments Group: Patented cell line.
Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C2010127.
Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:2608; CYP2A13.
Transformant: Ad12-SV40 hybrid virus.
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0168 (BEAS-2B)
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=22743290; DOI=10.1016/j.tox.2012.06.010
Xue-Jiao Yang, Hui-Yuan Lu, Zi-Yin Li, Qian Bian, Liang-Lin Qiu, Zhong Li, Qi-Zhan Liu, Jian-Min Li, Xin-Ru Wang, Shou-Lin Wang;
Cytochrome P450 2A13 mediates aflatoxin B1-induced cytotoxicity and apoptosis in human bronchial epithelial cells.
Toxicology 300:138-148(2012)

Patent=CN102168061B
Shou-Lin Wang, Hui-Yuan Lu, Zi-Yin Li, Jian-Min Li, Xue-Jiao Yang;
Human lung cell BEAS-2B/CYP2A13, and preparation method and application thereof.
Patent number CN102168061B, 22-May-2013

PubMed=23602888; DOI=10.1016/j.taap.2013.04.005
Xue-Jiao Yang, Zhan Zhang, Xi-Chen Wang, Yun Wang, Xiao-Ming Zhang, Hui-Yuan Lu, Shou-Lin Wang;
Cytochrome P450 2A13 enhances the sensitivity of human bronchial epithelial cells to aflatoxin B1-induced DNA damage.
Toxicol. Appl. Pharmacol. 270:114-121(2013)

PubMed=24114584; DOI=10.1002/ijc.28489
Zhan Zhang, Hui-Yuan Lu, Fei Huan, Cromie Meghan, Xue-Jiao Yang, Yun Wang, Xi-Chen Wang, Xin-Ru Wang, Shou-Lin Wang;
Cytochrome P450 2A13 mediates the neoplastic transformation of human bronchial epithelial cells at a low concentration of aflatoxin B1.
Int. J. Cancer 134:1539-1548(2014)

Cross-references
Cell line databases/resources CCRID; 4201PAT-CCTCC00427
Encyclopedic resources Wikidata; Q93425306
Entry history
Entry creation06-Sep-2019
Last entry update10-Apr-2025
Version number12