Cellosaurus cell line 8724 (CVCL

Cellosaurus 8724 (CVCL_WZ11)

[Text version]

Cell line name

8724

Accession

CVCL_WZ11

Resource Identification Initiative

To cite this cell line use: 8724 (RRID:CVCL_WZ11)

Comments

Omics: Genomics; Whole genome sequencing; Low read coverage.
Omics: Transcriptomics; RNAseq.
Miscellaneous: Age at sampling from personal communication of Castillo-Tong, Dan Cacsire.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.

Sequence variations

Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Thr3013Ile (c.9038C>T); ClinVar=VCV000038205; Zygosity=Unspecified (PubMed=31150822).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.His179Tyr (c.535C>T); ClinVar=VCV000127815; Zygosity=Unspecified (PubMed=31150822).

Disease

High grade ovarian serous adenocarcinoma (NCIt: C105555)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

68Y

Category

Cancer cell line

STR profile

Source(s): PubMed=31150822

Markers:

Amelogenin	X
CSF1PO	10
D1S1656	14,16.3
D2S1338	18,21
D3S1358	15,17
D5S818	13
D6S1043	13
D7S820	9,10
D8S1179	11,15
D12S391	16,22
D13S317	12
D16S539	9,12
D18S51	13
D19S433	15,15.2
D21S11	27,31.2
FGA	21
Penta D	12,13
Penta E	7,19
TH01	9.3
TPOX	8,9
vWA	14,18

Publications

PubMed=31150822; DOI=10.1016/j.canlet.2019.05.032
Caroline Kreuzinger, Isabel von der Decken, Andrea Wolf, Magdalena Gamperl, Julia Koller, Jasmine Karacs, Stephanie Pfaffinger, Thomas Bartl, Alexander Reinthaller, Christoph Grimm, Christian F. Singer ...Show all 21 authors... , Elena Ioana Braicu, Paula Cunnea, Charlie Gourley, Dominiek Smeets, Bram Boeckx, Diether Lambrechts, Paul Perco, Reinhard Horvat, Els M.J.J. Berns, Dan Cacsire Castillo-Tong; Show fewer authors
Patient-derived cell line models revealed therapeutic targets and molecular mechanisms underlying disease progression of high grade serous ovarian cancer.
Cancer Lett. 459:1-12(2019)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_WZ11

Encyclopedic resources

Wikidata; Q93310425

Entry history

Entry creation

06-Sep-2019

Last entry update

10-Apr-2025

Version number