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Cellosaurus 54BR (CVCL_WY85)

[Text version]
Cell line name 54BR
Synonyms 54 BRighton
Accession CVCL_WY85
Resource Identification Initiative To cite this cell line use: 54BR (RRID:CVCL_WY85)
Comments Doubling time: 45.9 hours (PubMed=6459055).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 50Y
Category Finite cell line
Publications

PubMed=11219864; DOI=10.1093/carcin/1.9.745
Colin Francis Arlett, Susan A. Harcourt, Alan R. Lehmann, Sean Stevens, Malcolm Andrew Ferguson-Smith, W. Neil Morley;
Studies on a new case of xeroderma pigmentosum (XP3BR) from complementation group G with cellular sensitivity to ionizing radiation.
Carcinogenesis 1:745-751(1980)

PubMed=6459055; DOI=10.1111/j.1469-1809.1981.tb00320.x
Joy Dorothy Ann Delhanty, Jennifer M. Parrington, Graham Casey, John Attwood, Lyndsay West, David Kirk, Gerald Corney;
Growth, DNA repair, sister chromatid exchange and chromosome studies in fibroblasts from Huntington's disease patients.
Ann. Hum. Genet. 45:181-198(1981)

PubMed=7067035; DOI=10.1093/carcin/3.1.33
Ian A. Teo, Colin Francis Arlett;
The response of a variety of human fibroblast cell strains to the lethal effects of alkylating agents.
Carcinogenesis 3:33-37(1982)

DOI=10.1007/978-1-4757-1117-2_12
Colin Francis Arlett, Susan A. Harcourt;
The mutagen sensitivity response of cells from individuals heterozygous for DNA repair deficiency genes.
(In book chapter) The use of human cells for the evaluation of risk from physical and chemical agents; Castellani, Amleto (eds.); pp.155-167; Springer; Boston; USA (1983)

PubMed=6307543; DOI=10.1093/carcin/4.8.1075
Ian A. Teo, Alan R. Lehmann, R. Muller, Manfred Fedor Rajewsky;
Similar rate of O6-ethylguanine elimination from DNA in normal human fibroblast and xeroderma pigmentosum cell strains not transformed by SV40.
Carcinogenesis 4:1075-1077(1983)

PubMed=2903889; DOI=10.1080/09553008814552321
Colin Francis Arlett, Michael H.L. Green, Anne Priestley, Susan A. Harcourt, Lynne V. Mayne;
Comparative human cellular radiosensitivity: I. The effect of SV40 transformation and immortalisation on the gamma-irradiation survival of skin derived fibroblasts from normal individuals and from ataxia-telangiectasia patients and heterozygotes.
Int. J. Radiat. Biol. 54:911-928(1988)

Cross-references
Encyclopedic resources Wikidata; Q93307797
Entry history
Entry creation06-Sep-2019
Last entry update29-Jun-2023
Version number6