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Cellosaurus TR30-9 (CVCL_WY39)

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Cell line name TR30-9
Accession CVCL_WY39
Resource Identification Initiative To cite this cell line use: TR30-9 (RRID:CVCL_WY39)
Comments Population: Lebanese.
Characteristics: Wild type transfected POLH can be expressed upon addition of tetracycline.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:9181; POLH.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:9181; POLH; Simple; p.Ala35fs (c.104_116del); Zygosity=Homozygous (from parent cell line).
Disease Xeroderma pigmentosum variant type (NCIt: C141367)
Xeroderma pigmentosum variant (ORDO: Orphanet_90342)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7395 (XP30RO)
Sex of cell Male
Age at sampling 30Y
Category Finite cell line
Publications

PubMed=16520097; DOI=10.1016/j.dnarep.2006.01.008
Severine Cruet-Hennequart, Seamus Coyne, Macdara T. Glynn, Gregory G. Oakley, Michael P. Carty;
UV-induced RPA phosphorylation is increased in the absence of DNA polymerase eta and requires DNA-PK.
DNA Repair 5:491-504(2006)

Cross-references
Encyclopedic resources Wikidata; Q98133528
Entry history
Entry creation06-Sep-2019
Last entry update19-Dec-2024
Version number10