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Cellosaurus CJ179-hTERT (CVCL_WY32)

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Cell line name CJ179-hTERT
Synonyms CJ179 hTERT; CJ179 hTert; CJ179hTERT; CJ179hTert
Accession CVCL_WY32
Resource Identification Initiative To cite this cell line use: CJ179-hTERT (RRID:CVCL_WY32)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11730; TERT.
Cell type: Fibroblast; CL=CL_0000057.
Disease Severe combined immunodeficiency, Athabascan type (NCIt: C162694)
Severe combined immunodeficiency due to DCLRE1C deficiency (ORDO: Orphanet_275)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_WY31 (CJ179)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Telomerase immortalized cell line
Publications

PubMed=15574327; DOI=10.1016/j.molcel.2004.10.029
Enriqueta Riballo, Martin Kuhne, Nicole Rief, Aidan J. Doherty, Graeme C.M. Smith, Maria-Jose Recio, Caroline Reis, Kirsten Dahm, Andreas Fricke, Andrea Krempler, Antony R. Parker ...Show all 15 authors... , Stephen Philip Jackson, Andrew R. Gennery, Penelope Ann Jeggo, Markus Lobrich; Show fewer authors
A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.
Mol. Cell 16:715-724(2004)

PubMed=16540517; DOI=10.1093/hmg/ddl050
Paul M. Evans, Lisa Woodbine, Enriqueta Riballo, Andrew R. Gennery, Michael Hubank, Penelope Ann Jeggo;
Radiation-induced delayed cell death in a hypomorphic Artemis cell line.
Hum. Mol. Genet. 15:1303-1311(2006)

PubMed=16874298; DOI=10.1038/sj.emboj.7601255; PMCID=PMC1553186
Aaron A. Goodarzi, Ya-Ping Yu, Enriqueta Riballo, Pauline Douglas, Sarah A. Walker, Rui-Qiong Ye, Christine Harer, Caterina Marchetti, Nick Morrice, Penelope Ann Jeggo, Susan P. Lees-Miller;
DNA-PK autophosphorylation facilitates Artemis endonuclease activity.
EMBO J. 25:3880-3889(2006)

Cross-references
Encyclopedic resources Wikidata; Q93453840
Entry history
Entry creation06-Sep-2019
Last entry update19-Dec-2024
Version number9