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Cellosaurus GH4T2 (CVCL_WX20)

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Cell line name GH4T2
Synonyms GH4 T2
Accession CVCL_WX20
Resource Identification Initiative To cite this cell line use: GH4T2 (RRID:CVCL_WX20)
Comments Characteristics: Produced from a tumor produced by the passage of the parent cell line through female Wistar Furth rats (PubMed=1620544).
Derived from site: In situ; Pituitary gland; UBERON=UBERON_0000007.
Disease Rat pituitary gland neoplasm (NCIt: C132194)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Wistar Furth; RS=RS_0000982.
Hierarchy Parent: CVCL_0276 (GH4C1)
Sex of cell Female
Age at sampling 7M
Category Cancer cell line
Publications

PubMed=1620544
Kerry E. Conrad, Arthur Gutierrez-Hartmann;
The ras and protein kinase A pathways are mutually antagonistic in regulating rat prolactin promoter activity.
Oncogene 7:1279-1286(1992)

PubMed=9388230; DOI=10.1074/jbc.272.49.30852
Rebecca E. Schweppe, Ashley Ann Frazer-Abel, Arthur Gutierrez-Hartmann, Andrew Peter Bradford;
Functional components of fibroblast growth factor (FGF) signal transduction in pituitary cells. Identification of FGF response elements in the prolactin gene.
J. Biol. Chem. 272:30852-30859(1997)

PubMed=11518800; DOI=10.1210/mend.15.9.0683
Twila A. Jackson, Rebecca E. Schweppe, David M. Koterwas, Andrew Peter Bradford;
Fibroblast growth factor activation of the rat PRL promoter is mediated by PKCdelta.
Mol. Endocrinol. 15:1517-1528(2001)

Cross-references
Encyclopedic resources Wikidata; Q93560965
Entry history
Entry creation06-Sep-2019
Last entry update10-Apr-2025
Version number7