• Mutation; RGD; 3205; Nras; Simple; p.Gly13Val (c.38_39GC>TT); Zygosity=Unspecified (from inference of genetic background of other Eker-derived cell lines).
  
• Mutation; RGD; 3205; Nras; Simple; p.Val14Ile (c.40G>A); Zygosity=Unspecified (from inference of genetic background of other Eker-derived cell lines).
  
• Mutation; RGD; 3205; Nras; Simple; p.Ala18Val (c.53C>T); Zygosity=Unspecified (from inference of genetic background of other Eker-derived cell lines).
  
• Mutation; RGD; 3908; Tsc2; Simple; p.Val1272fs; Zygosity=Heterozygous; Note=Insertion of a 5 kb retrotransposon (from inference of genetic background of other Eker-derived cell lines).
  

CLPUB00521
Jerome J. Freed, Sharon Howard, Anthony V. Lerro, Lori A. Dodson, D. Sesok, Alfred George Knudson Jr.;
Hereditary renal tumors in the rat: cell lines from adenocarcinomas induced by the Eker mutation.
Proc. Am. Assoc. Cancer Res. 31:317-317(1990)

PubMed=8419937; DOI=10.1073/pnas.90.1.327; PMCID=PMC45653
Okio Hino, Andres J.P. Klein-Szanto, Jerome J. Freed, Joseph R. Testa, Darrell Q. Brown, Maria Vilensky, Raymond S.W. Yeung, Kenneth D. Tartof, Alfred George Knudson Jr.;
Spontaneous and radiation-induced renal tumors in the Eker rat model of dominantly inherited cancer.
Proc. Natl. Acad. Sci. U.S.A. 90:327-331(1993)

PubMed=7559744; DOI=10.1007/BF01197777
Okio Hino, Eisuko Kobayashi, Masae Nishizawa, Yoshihiro Kubo, Toshiyuki Kobayashi, Youko Hirayama, Shunsuke Takai, Yasushi Kikuchi, Haruo Tsuchiya, Kenji Orimoto, Kazunori Kajino, Terumi Takahara;
Renal carcinogenesis in the Eker rat.
J. Cancer Res. Clin. Oncol. 121:602-605(1995)

PubMed=11011112; DOI=10.1111/j.1349-7006.2000.tb01027.x; PMCID=PMC5926447
Shuichi Majima, Kazunori Kajino, Tomokazu Fukuda, Fujio Otsuka, Okio Hino;
A novel gene 'Niban' upregulated in renal carcinogenesis: cloning by the cDNA-amplified fragment length polymorphism approach.
Jpn. J. Cancer Res. 91:869-874(2000)