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Cellosaurus BT422 (CVCL_WW65)

[Text version]
Cell line name BT422
Synonyms BT 422; CCLF-KL1254; CCLF_KL1254; CPDM_0888X
Accession CVCL_WW65
Resource Identification Initiative To cite this cell line use: BT422 (RRID:CVCL_WW65)
Comments Part of: Cancer Cell Line Factory (CCLF) cell models.
Part of: Center for Patient Derived Models (CPDM) at Dana-Farber Cancer Institute cell line panel.
Population: Caucasian.
Characteristics: Low-passage-number culture.
Characteristics: Can grow as a neurosphere (PubMed=34610309).
Omics: Genomics; Whole exome sequencing.
Omics: Genomics; Whole genome sequencing; Low read coverage.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Brain, left frontal cortex; UBERON=UBERON_0001870.
Disease Astrocytoma, IDH-mutant, grade 4 (NCIt: C167335)
Diffuse astrocytoma (ORDO: Orphanet_251595)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 72Y
Category Cancer cell line
Web pages Provider; CPDM; CPDM_0888X; https://docs.google.com/spreadsheets/d/1sxAPF3p6xK2h01zaiQ1ExCWwzhxeZ-oDLN3s3LeJq98/edit?usp=sharing
Publications

PubMed=34610309; DOI=10.1016/j.celrep.2021.109788
Stockslager M.A., Malinowski S., Touat M., Yoon J.C., Geduldig J., Mirza M., Kim A.S., Wen P.Y.-C., Chow K.-H., Ligon K.L., Manalis S.R.
Functional drug susceptibility testing using single-cell mass predicts treatment outcome in patient-derived cancer neurosphere models.
Cell Rep. 37:109788.1-109788.12(2021)

Cross-references
Chemistry resources PharmacoDB; BT422_141_2019
Encyclopedic resources Wikidata; Q93432639
Entry history
Entry creation06-Sep-2019
Last entry update10-Apr-2025
Version number6