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Cellosaurus BT248 (CVCL_WW55)

[Text version]
Cell line name BT248
Synonyms BT 248; CPDM_1292X
Accession CVCL_WW55
Resource Identification Initiative To cite this cell line use: BT248 (RRID:CVCL_WW55)
Comments Part of: Center for Patient Derived Models (CPDM) at Dana-Farber Cancer Institute cell line panel.
Population: Caucasian.
Characteristics: Low-passage-number culture.
Characteristics: Can grow as a neurosphere (PubMed=34610309).
Omics: Genomics; Whole exome sequencing.
Omics: Genomics; Whole genome sequencing; Low read coverage.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Brain, right temporal cortex; UBERON=UBERON_0016538.
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 62Y
Category Cancer cell line
Web pages Provider; CPDM; CPDM_1292X; https://docs.google.com/spreadsheets/d/1sxAPF3p6xK2h01zaiQ1ExCWwzhxeZ-oDLN3s3LeJq98/edit?usp=sharing
Publications

PubMed=25184684; DOI=10.1371/journal.pone.0106694; PMCID=PMC4153667
Holmberg Olausson K., Maire C.L., Haidar S., Ling J., Learner E., Nister M., Ligon K.L.
Prominin-1 (CD133) defines both stem and non-stem cell populations in CNS development and gliomas.
PLoS ONE 9:e106694.1-e106694.11(2014)

PubMed=34610309; DOI=10.1016/j.celrep.2021.109788
Stockslager M.A., Malinowski S., Touat M., Yoon J.C., Geduldig J., Mirza M., Kim A.S., Wen P.Y.-C., Chow K.-H., Ligon K.L., Manalis S.R.
Functional drug susceptibility testing using single-cell mass predicts treatment outcome in patient-derived cancer neurosphere models.
Cell Rep. 37:109788.1-109788.12(2021)

Cross-references
Chemistry resources PharmacoDB; BT248_131_2019
Encyclopedic resources Wikidata; Q93432617
Entry history
Entry creation06-Sep-2019
Last entry update10-Apr-2025
Version number6