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Cellosaurus BT231 (CVCL_WW52)

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Cell line name BT231
Synonyms BT 231; CPDM_2087
Accession CVCL_WW52
Resource Identification Initiative To cite this cell line use: BT231 (RRID:CVCL_WW52)
Comments Part of: Center for Patient Derived Models (CPDM) at Dana-Farber Cancer Institute cell line panel.
Characteristics: Low-passage-number culture.
Characteristics: Can grow as a neurosphere (PubMed=34610309).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling 82Y
Category Cancer cell line
Web pages Provider; CPDM; CPDM_2087; https://docs.google.com/spreadsheets/d/1sxAPF3p6xK2h01zaiQ1ExCWwzhxeZ-oDLN3s3LeJq98/edit?usp=sharing
Publications

PubMed=25184684; DOI=10.1371/journal.pone.0106694; PMCID=PMC4153667
Karl Holmberg Olausson, Cecile L. Maire, Samer Haidar, Jason Ling, Emily Learner, Monica Nister, Keith Lloyd Ligon;
Prominin-1 (CD133) defines both stem and non-stem cell populations in CNS development and gliomas.
PLoS ONE 9:e106694.1-e106694.11(2014)

PubMed=34610309; DOI=10.1016/j.celrep.2021.109788
Max A. Stockslager, Seth Malinowski, Mehdi Touat, Jennifer C. Yoon, Jack Geduldig, Mahnoor Mirza, Annette Sunhi Kim, Patrick Yung-Chih Wen, Kin-Hoe Chow, Keith Lloyd Ligon, Scott R. Manalis;
Functional drug susceptibility testing using single-cell mass predicts treatment outcome in patient-derived cancer neurosphere models.
Cell Rep. 37:109788.1-109788.12(2021)

Cross-references
Chemistry resources PharmacoDB; BT231_127_2019
Encyclopedic resources Wikidata; Q93432605
Entry history
Entry creation06-Sep-2019
Last entry update10-Apr-2025
Version number6