Cellosaurus cell line ITOC-04 (CVCL

Cellosaurus ITOC-04 (CVCL_WS69)

[Text version]

Cell line name

ITOC-04

Synonyms

Indian Tata memorial centre Oral Cancer-04

Accession

CVCL_WS69

Resource Identification Initiative

To cite this cell line use: ITOC-04 (RRID:CVCL_WS69)

Comments

Population: Indian.
Doubling time: 47.75 hours (PubMed=31164688).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.

Sequence variations

Mutation; HGNC; HGNC:11998; TP53; Simple; c.74+38C>G (IVS2+38C>G); ClinVar=VCV000137691; Zygosity=Unspecified (PubMed=31164688).
Mutation; HGNC; HGNC:11998; TP53; Simple; c.96+41_97-54delCTCCAGGTCCCCAGCC (c.96+41_96+56del16) (IVS3+36_52del16); ClinVar=VCV000440349; Zygosity=Unspecified (PubMed=31164688).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg342Ter (c.1024C>T); ClinVar=VCV000182970; Zygosity=Unspecified (PubMed=31164688).

Disease

Buccal mucosa squamous cell carcinoma (NCIt: C4040)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

61Y

Category

Cancer cell line

STR profile

Source(s): PubMed=31164688

Markers:

Amelogenin	X
CSF1PO	12
D5S818	10.1,12.3
D7S820	9.3,12
D13S317	11,13
D16S539	12.1
TH01	7,9.1
TPOX	10.3
vWA	13,15,17

Publications

PubMed=31164688; DOI=10.1038/s41598-019-44143-0; PMCID=PMC6547758
Kshama Pansare, Nilesh Gardi, Sayee Kamat, Prerana Dange, Rahul Previn, Poonam Gera, Pradnya K. Kowtal, Kishore Amin, Rajiv Sarin;
Establishment and genomic characterization of gingivobuccal carcinoma cell lines with smokeless tobacco associated genetic alterations and oncogenic PIK3CA mutation.
Sci. Rep. 9:8272.1-8272.10(2019)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_WS69

Encyclopedic resources

Wikidata; Q94325013

Entry history

Entry creation

05-Jul-2019

Last entry update

10-Apr-2025

Version number