Cellosaurus cell line ITOC-01 (CVCL

Cellosaurus ITOC-01 (CVCL_WS66)

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Cell line name

ITOC-01

Synonyms

Indian Tata memorial centre Oral Cancer-01

Accession

CVCL_WS66

Resource Identification Initiative

To cite this cell line use: ITOC-01 (RRID:CVCL_WS66)

Comments

Population: Indian.
Doubling time: 47.31 hours (PubMed=31164688).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.

Sequence variations

Mutation; HGNC; HGNC:7881; NOTCH1; Simple; p.Gln1214Ter (c.3640C>T); Zygosity=Unspecified (PubMed=31164688).
Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Unspecified (PubMed=31164688).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126His (c.376T>C); ClinVar=VCV001734755; Zygosity=Unspecified (PubMed=31164688).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Unspecified (PubMed=31164688).

Disease

Buccal mucosa squamous cell carcinoma (NCIt: C4040)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

28Y

Category

Cancer cell line

STR profile

Source(s): PubMed=31164688

Markers:

Amelogenin	X,Y
CSF1PO	10,12.1
D5S818	10
D7S820	9.3,12
D13S317	10,12
D16S539	13
TH01	5
TPOX	7.3
vWA	15.2,16.1

Publications

PubMed=31164688; DOI=10.1038/s41598-019-44143-0; PMCID=PMC6547758
Kshama Pansare, Nilesh Gardi, Sayee Kamat, Prerana Dange, Rahul Previn, Poonam Gera, Pradnya K. Kowtal, Kishore Amin, Rajiv Sarin;
Establishment and genomic characterization of gingivobuccal carcinoma cell lines with smokeless tobacco associated genetic alterations and oncogenic PIK3CA mutation.
Sci. Rep. 9:8272.1-8272.10(2019)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_WS66

Encyclopedic resources

Wikidata; Q94325005

Entry history

Entry creation

05-Jul-2019

Last entry update

10-Apr-2025

Version number