Cellosaurus cell line TCC-NECT-2 (CVCL

Cellosaurus TCC-NECT-2 (CVCL_WS42)

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Cell line name

TCC-NECT-2

Accession

CVCL_WS42

Resource Identification Initiative

To cite this cell line use: TCC-NECT-2 (RRID:CVCL_WS42)

Comments

Population: Japanese.
Doubling time: ~31.4 hours (PubMed=30559933).
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.

Sequence variations

Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=30559933).
Mutation; HGNC; HGNC:11998; TP53; Simple; c.783-1G>A; ClinVar=VCV000458565; Zygosity=Homozygous; Note=Splice acceptor mutation (PubMed=30559933).

Disease

Duodenal neuroendocrine tumor (NCIt: C135080)
Duodenal neuroendocrine tumor (ORDO: Orphanet_100076)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

59Y

Category

Cancer cell line

STR profile

Source(s): JCRB=JCRB1916

Markers:

Amelogenin	X
CSF1PO	13
D5S818	11
D7S820	10
D13S317	9,11
D16S539	10,13
TH01	9
TPOX	8
vWA	18,20

Publications

PubMed=29765522; DOI=10.18632/oncotarget.24930; PMCID=PMC5940407
Akihiro Ohmoto, Masami Suzuki, Erina Takai, Hirofumi Rokutan, Yuko Fujiwara, Chigusa Morizane, Kazuyoshi Yanagihara, Tatsuhiro Shibata, Shinichi Yachida;
Establishment of preclinical chemotherapy models for gastroenteropancreatic neuroendocrine carcinoma.
Oncotarget 9:21086-21099(2018)

PubMed=30559933; DOI=10.18632/oncotarget.26367; PMCID=PMC6284856
Kazuyoshi Yanagihara, Takanori Kubo, Keichiro Mihara, Takeshi Kuwata, Atsushi Ochiai, Toshio Seyama, Hiroshi Yokozaki;
Establishment of a novel cell line from a rare human duodenal poorly differentiated neuroendocrine carcinoma.
Oncotarget 9:36503-36514(2018)

Cross-references

Cell line collections (Providers)

JCRB; JCRB1916

Cell line databases/resources

cancercelllines; CVCL_WS42

Encyclopedic resources

Wikidata; Q98133180

Entry history

Entry creation

05-Jul-2019

Last entry update

19-Dec-2024

Version number