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Cellosaurus LN-2207GS (CVCL_WS27)

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Cell line name LN-2207GS
Accession CVCL_WS27
Resource Identification Initiative To cite this cell line use: LN-2207GS (RRID:CVCL_WS27)
Comments Characteristics: Glioma-derived sphere line. Non-tumorigenic in nude mice.
Omics: Genomics; DNA methylation analysis.
Omics: Transcriptomics; Microarray.
Omics: Variations; Array-based CGH.
Miscellaneous: STR profile from personal communication of Gusyatiner, Olga.
Derived from site: In situ; Brain, left parietal lobe; UBERON=UBERON_0002802.
Sequence variations
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_S442 ! LN-2207
Sex of cell Male
Age at sampling 42Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX,Y
CSF1PO10,11,12
D1S165617.3
D2S44111
D2S133819,25
D3S135814,16
D5S81811,12
D7S8208
D8S117911,13
D10S124814
D12S39118,19
D13S31711,12
D16S53912
D18S5111,14
D19S43313,14
D21S1130,31
D22S104515,16
DYS39110
DYS57018
DYS57617
FGA22,23
Penta D12,13
Penta E11,12
SE3317
TH017,9
TPOX8,9
vWA16,17

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Publications

PubMed=21097691; DOI=10.1158/1078-0432.CCR-10-1931
Davide Sciuscio, Annie-Claire Diserens, Kristof van Dommelen, Danielle Martinet, Greg Jones, Robert-Charles Janzer, Claudio Pollo, Marie-France Hamou, Bernd Kaina, Roger Stupp, Marc Levivier, Monika E. Hegi;
Extent and patterns of MGMT promoter methylation in glioblastoma- and respective glioblastoma-derived spheres.
Clin. Cancer Res. 17:255-266(2011)

PubMed=22570425; DOI=10.1093/neuonc/nos072; PMCID=PMC3367844
Pierre Bady, Annie-Claire Diserens, Vincent Castella, Stefanie Kalt, Karl Heinimann, Marie-France Hamou, Mauro Delorenzi, Monika E. Hegi;
DNA fingerprinting of glioma cell lines and considerations on similarity measurements.
Neuro-oncol. 14:701-711(2012)

PubMed=25622821; DOI=10.1186/s13059-015-0583-7; PMCID=PMC4342872
Sebastian Kurscheid, Pierre Bady, Davide Sciuscio, Ivana Samarzija, Tal Shay, Irene Vassallo, Wim Van Criekinge, Roy Thomas Daniel, Martin J. van den Bent, Christine Marosi, Michael Weller ...Show all 16 authors... , Warren P. Mason, Eytan Domany, Roger Stupp, Mauro Delorenzi, Monika E. Hegi; Show fewer authors
Chromosome 7 gain and DNA hypermethylation at the HOXA10 locus are associated with expression of a stem cell related HOX-signature in glioblastoma.
Genome Biol. 16:16.1-16.15(2015)

Cross-references
Encyclopedic resources Wikidata; Q95982660
Gene expression databases GEO; GSM1469038
GEO; GSM2794458
GEO; GSM2794459
GEO; GSM2794460
GEO; GSM2889486
Entry history
Entry creation05-Jul-2019
Last entry update10-Apr-2025
Version number10