Cellosaurus logo
expasy logo

Cellosaurus OSE-MG63 (CVCL_WR53)

[Text][XML][JSON]
Cell line name OSE-MG63
Accession CVCL_WR53
Resource Identification Initiative To cite this cell line use: OSE-MG63 (RRID:CVCL_WR53)
Comments Population: Caucasian.
Characteristics: Transfected with a construct containing 6 tandem repeats of the osteoblastic specific element 2 (OSE2) and a minimal mOG2 promoter upstream of eGFP.
Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Derived from site: Metastatic; Bone, left femur; UBERON=UBERON_0000981.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0426 (MG-63)
Sex of cell Male
Age at sampling 14Y
Category Cancer cell line
Publications

PubMed=23675497; DOI=10.1371/journal.pone.0063661; PMCID=PMC3651164
Zhong-Quan Dai, Feng Wu, Jian Chen, Hong-Jie Xu, Hong-Hui Wang, Fei-Ma Guo, Ying-Jun Tan, Bai Ding, Jin-Fu Wang, Yu-Min Wan, Ying-Hui Li;
Actin microfilament mediates osteoblast Cbfa1 responsiveness to BMP2 under simulated microgravity.
PLoS ONE 8:e63661.1-e63661.10(2013)

Cross-references
Encyclopedic resources Wikidata; Q98128381
Entry history
Entry creation05-Jul-2019
Last entry update19-Dec-2024
Version number9