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Cellosaurus NK101 (CVCL_WN95)

[Text version]
Cell line name NK101
Accession CVCL_WN95
Resource Identification Initiative To cite this cell line use: NK101 (RRID:CVCL_WN95)
Comments Population: Korean.
Characteristics: Possesses fundamental characteristics of natural killer NK (cells). Potential to simultaneously act as a cytokine producer and a cytotoxic effector.
Doubling time: 21.9 +- 2.4 hours (PubMed=31126350).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Transcriptomics; RNAseq.
Miscellaneous: STR profile from personal communication of Kim, Sae Won.
Disease Nasal type extranodal NK/T-cell lymphoma (NCIt: C4684)
Extranodal nasal NK/T cell lymphoma (ORDO: Orphanet_86879)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX
CSF1PO11,12
D2S133820,24
D3S135816
D5S81810,11
D7S8209,12
D8S117911,15
D13S31710,12
D16S53911,12
D18S5112,13
D19S43314
D21S1131.2,32.2
FGA21,24
TH017,9
TPOX11
vWA14,16

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Publications

PubMed=31126350; DOI=10.1186/s40425-019-0612-2; PMCID=PMC6534912
Yang H.G., Kang M.C., Kim T.Y., Hwang I., Jin H.T., Sung Y.C., Eom K.-S., Kim S.W.
Discovery of a novel natural killer cell line with distinct immunostimulatory and proliferative potential as an alternative platform for cancer immunotherapy.
J. Immunother. Cancer 7:138.1-138.17(2019)

Cross-references
Encyclopedic resources Wikidata; Q98127913
Entry history
Entry creation05-Jul-2019
Last entry update10-Apr-2025
Version number6