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Cellosaurus SP212Corr (CVCL_WN81)

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Cell line name SP212Corr
Accession CVCL_WN81
Resource Identification Initiative To cite this cell line use: SP212Corr (RRID:CVCL_WN81)
Comments Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:10801; SFTPB; Simple_corrected; p.Pro121Glufs*95 (c.361delCinsGAA) (121ins2); ClinVar=VCV000013201; Zygosity=Homozygous; Note=By CRISPR/Cas9 (PubMed=28965766).
Disease Pulmonary surfactant metabolism dysfunction-1 (NCIt: C99068)
Neonatal acute respiratory distress due to SP-B deficiency (ORDO: Orphanet_217563)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_WN80 (SP212)
Sex of cell Female
Age at sampling 5M
Category Induced pluripotent stem cell
Publications

PubMed=28965766; DOI=10.1016/j.stem.2017.08.014; PMCID=PMC5755620
Anjali Jacob, Michael Morley, Finn Hawkins, Katherine B. McCauley, Jyh-Chang Jean, Hillary B. Heins, Cheng-Lun Na, Timothy E. Weaver, Marall Vedaie, Killian Hurley, Anne Hinds ...Show all 27 authors... , Scott J. Russo, Seunghyi Kook, William Zacharias, Matthias Ochs, Katrina Traber, Lee J. Quinton, Ana M. Crane, Brian R. Davis, Frances V. White, Jennifer Wambach, Jeffrey A. Whitsett, F. Sessions Cole, Edward E. Morrisey, Susan H. Guttentag, Michael F. Beers, Darrell N. Kotton; Show fewer authors
Differentiation of human pluripotent stem cells into functional lung alveolar epithelial cells.
Cell Stem Cell 21:472-488.e10(2017)

Cross-references
Encyclopedic resources Wikidata; Q98132806
Entry history
Entry creation24-May-2019
Last entry update19-Dec-2024
Version number8