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Cellosaurus SV40-T2 (CVCL_WN19)

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Cell line name SV40-T2
Synonyms SV40T2
Accession CVCL_WN19
Resource Identification Initiative To cite this cell line use: SV40-T2 (RRID:CVCL_WN19)
Comments Doubling time: 22 hours (PubMed=1716583).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Lung, alveolus; UBERON=UBERON_0002299.
Cell type: Type 2 pneumocyte; CL=CL_0002063.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Sprague Dawley; RS=RS_0000681.
Sex of cell Sex unspecified
Age at sampling 8-10D
Category Transformed cell line
Publications

PubMed=1716583; DOI=10.1016/0014-4827(91)90251-O
Annick Clement, Mark P. Steele, Jerome S. Brody, Norbert G. Riedel;
SV40T-immortalized lung alveolar epithelial cells display post-transcriptional regulation of proliferation-related genes.
Exp. Cell Res. 196:198-205(1991)

PubMed=8841424; DOI=10.1002/(SICI)1097-4652(199610)169:1<78::AID-JCP8>3.0.CO;2-B
Patrick Michaut, Carole Planes, Brigitte Escoubet, Annick Clement, Claude Amiel, Christine Clerici;
Rat lung alveolar type II cell line maintains sodium transport characteristics of primary culture.
J. Cell. Physiol. 169:78-86(1996)

PubMed=20135361; DOI=10.1007/s11626-009-9269-3
Yutaka Yamada, Akifumi Nakata, Mitsuaki A. Yoshida, Yoshiya Shimada, Yoichi Oghiso, Jean-Luc Poncy;
Implication of p16 inactivation in tumorigenic activity of respiratory epithelial cell lines and adenocarcinoma cell line established from plutonium-induced lung tumor in rat.
In Vitro Cell. Dev. Biol. Anim. 46:477-486(2010)

Cross-references
Encyclopedic resources Wikidata; Q98132895
Entry history
Entry creation24-May-2019
Last entry update14-Aug-2025
Version number10