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Cellosaurus PC3-R-caba (CVCL_WM76)

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Cell line name PC3-R-caba
Accession CVCL_WM76
Resource Identification Initiative To cite this cell line use: PC3-R-caba (RRID:CVCL_WM76)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_63584; Cabazitaxel.
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0035 (PC-3)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
Publications

PubMed=27198502; DOI=10.15252/emmm.201506059; PMCID=PMC4931290
Nader Al Nakouzi, Chris Ke-Dong Wang, Eliana Beraldi, Wolfgang Jager, Susan Ettinger, Ladan Fazli, Lucia Nappi, Jennifer L. Bishop, Fan Zhang, Anne Chauchereau, Yohann Loriot, Martin E. Gleave;
Clusterin knockdown sensitizes prostate cancer cells to taxane by modulating mitosis.
EMBO Mol. Med. 8:761-778(2016)

Cross-references
Cell line databases/resources cancercelllines; CVCL_WM76
Encyclopedic resources Wikidata; Q98128508
Entry history
Entry creation24-May-2019
Last entry update19-Dec-2024
Version number8