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Cellosaurus NCI-H82-A (CVCL_WM70)

[Text version]
Cell line name NCI-H82-A
Synonyms NCI-H82A
Accession CVCL_WM70
Resource Identification Initiative To cite this cell line use: NCI-H82-A (RRID:CVCL_WM70)
Comments Population: Caucasian.
Characteristics: Established from parent cell line by selection of the adherent cells.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; HGNC:7577; MYH7 + HGNC; HGNC:9709; PVT1; Name(s)=PVT1-MYH7 (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Thr125Thr (c.375G>T); ClinVar=VCV000237948; Zygosity=Unspecified; Note=Impairs TP53 splicing dramatically (from parent cell line).
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1591 (NCI-H82)
Sex of cell Male
Age at sampling 41Y
Category Cancer cell line
Publications

PubMed=2473086; DOI=10.1242/jcs.91.1.91
Jos L.V. Broers, Mirjam Klein Rot, Tineke Oostendorp, Gerold Bepler, Lou F.M.H. de Leij, Desmond Niall Carney, Gijsbert Peter Vooijs, Frans C.S. Ramaekers;
Spontaneous changes in intermediate filament protein expression patterns in lung cancer cell lines.
J. Cell Sci. 91:91-108(1988)

PubMed=7720728
Nicole H.M. Senden, Helgi J.K. van de Velde, Jos L.V. Broers, Erika D.J. Timmer, Helma J.H. Kuijpers, Anton J.M. Roebroek, Wim J.M. van de Ven, Frans C.S. Ramaekers;
Subcellular localization and supramolecular organization of neuroendocrine-specific protein B (NSP-B) in small cell lung cancer.
Eur. J. Cell Biol. 65:341-353(1994)

Cross-references
Cell line databases/resources cancercelllines; CVCL_WM70
Encyclopedic resources Wikidata; Q95993676
Entry history
Entry creation24-May-2019
Last entry update19-Dec-2024
Version number11