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Cellosaurus 2211M (CVCL_WM38)

[Text version]
Cell line name 2211M
Accession CVCL_WM38
Resource Identification Initiative To cite this cell line use: 2211M (RRID:CVCL_WM38)
Comments Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=15195137).
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=15195137).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Pro246Ser (c.737C>T); Zygosity=Unspecified (PubMed=15195137).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser127Phe (c.380_381CC>TT); Zygosity=Unspecified (PubMed=15195137).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 41Y
Category Cancer cell line
Publications

PubMed=15195137; DOI=10.1038/sj.onc.1207780
Maria Daniotti, Maria Oggionni, Tiziana Ranzani, Viviana Vallacchi, Valentina Campi, Delia Di Stasi, Gabriella Della Torre, Federica Perrone, Chiara Luoni, Simona Suardi, Milo Frattini ...Show all 17 authors... , Silvana Pilotti, Andrea Anichini, Gabrina Tragni, Giorgio Parmiani, Marco Alessandro Pierotti, Monica Rodolfo; Show fewer authors
BRAF alterations are associated with complex mutational profiles in malignant melanoma.
Oncogene 23:5968-5977(2004)

Cross-references
Cell line databases/resources cancercelllines; CVCL_WM38
Encyclopedic resources Wikidata; Q93302168
Polymorphism and mutation databases Cosmic; 852213
IARC_TP53; 20613
Entry history
Entry creation24-May-2019
Last entry update19-Dec-2024
Version number10