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Cellosaurus GNM (CVCL_WL58)

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Cell line name GNM
Synonyms Gingival carcinoma Neck Metastasis
Accession CVCL_WL58
Resource Identification Initiative To cite this cell line use: GNM (RRID:CVCL_WL58)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=26116706). Originally thought to originate from a patient with a gingival carcinoma neck metastasis.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): PubMed=26116706

Markers:
AmelogeninX
CSF1PO9,10
D2S133817
D3S135815,18
D5S81811,12
D6S104318,19
D7S8208,12
D8S117912,13
D12S39120,25
D13S31712,13.3
D16S5399,10
D18S5116
D19S43313,14
D21S1127,28
FGA21
Penta D8,15
Penta E7,17
TH017
TPOX8,12
vWA16,18

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Publications

PubMed=10779629; DOI=10.1016/S0304-3835(00)00389-X
Yean-Jang Lee, Pel-Hu Liao, Wen-Kang Chen, Chi-Chiang Yang;
Preferential cytotoxicity of caffeic acid phenethyl ester analogues on oral cancer cells.
Cancer Lett. 153:51-56(2000)

PubMed=15929393
Chi-Ruei Huang, Shih-Shen Lin, Ming-Yung Chou, Chuan-Chen Ho, Li-Na Wang, Yin-Lau Lee, Chung-Shih Chen, Chi-Chiang Yang;
Demonstration of different modes of cell death upon herpes simplex virus 1 infection in different types of oral cells.
Acta Virol. 49:7-15(2005)

PubMed=26116706; DOI=10.1096/fj.14-266718
Fang Ye, Chu-Guang Chen, Jian Qin, Jie Liu, Cong-Yi Zheng;
Genetic profiling reveals an alarming rate of cross-contamination among human cell lines used in China.
FASEB J. 29:4268-4272(2015)

Cross-references
Cell line collections (Providers) CCTCC; GDC0185
Encyclopedic resources Wikidata; Q93934197
Entry history
Entry creation24-May-2019
Last entry update10-Apr-2025
Version number8