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Cellosaurus extEqFL (CVCL_WL35)

[Text version]
Cell line name extEqFL
Synonyms extended-lifespan Equine Fetal Liver
Accession CVCL_WL35
Resource Identification Initiative To cite this cell line use: extEqFL (RRID:CVCL_WL35)
Comments Senescence: Has an extended life span, but it is not sure if it is immortal.
Virology: Susceptible to infection by equine herpesvirus type 2 (EHV-2) and equine herpesvirus type 5 (EHV-5).
Doubling time: ~24 hours (Direct_author_submission).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Miscellaneous: Doubling time, sex of donor and breed of donor from personal communication of Thorsteinsdottir, Lilja.
Derived from site: In situ; Fetal liver; UBERON=UBERON_0002107.
Species of origin Equus caballus (Horse) (NCBI Taxonomy: 9796)
Breed/subspecies: Icelandic; VBO=VBO_0000991.
Originate from same individual CVCL_WL34 ! extEqFK
Sex of cell Female
Age at sampling 5FM
Category Transformed cell line
Publications

PubMed=27173610; DOI=10.1007/s11626-016-0046-9
Lilja Thorsteinsdottir, Sigurbjorg Torsteinsdottir, Vilhjalmur Svansson;
Establishment and characterization of fetal equine kidney and lung cells with extended lifespan. Susceptibility to equine gammaherpesvirus infection and transfection efficiency.
In Vitro Cell. Dev. Biol. Anim. 52:872-877(2016)

Cross-references
Cell line collections (Providers) ABM; T0095
Encyclopedic resources Wikidata; Q93547467
Entry history
Entry creation24-May-2019
Last entry update14-Aug-2025
Version number12