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Cellosaurus BT-1 (CVCL_WK81)

[Text version]
Cell line name BT-1
Synonyms Bovine Trophoblast-1
Accession CVCL_WK81
Resource Identification Initiative To cite this cell line use: BT-1 (RRID:CVCL_WK81)
Comments Doubling time: ~2.72 days (Note=In fibroblast-conditioned medium), ~2.97 days (Note=In 10% FBS) (PubMed=11504534).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Trophoblast; UBERON=UBERON_0000088.
Species of origin Bos taurus (Bovine) (NCBI Taxonomy: 9913)
Hierarchy Children:
CVCL_D5HN (BT-1S)
Sex of cell Sex unspecified
Age at sampling Blastocyst stage
Category Finite cell line
Publications

PubMed=11504534; DOI=10.1053/plac.2001.0702
Arata Shimada, Haruo Nakano, Toru Takahashi, Kei Imai, Kazuyoshi Hashizume;
Isolation and characterization of a bovine blastocyst-derived trophoblastic cell line, BT-1: development of a culture system in the absence of feeder cell.
Placenta 22:652-662(2001)

PubMed=15613779; DOI=10.1262/jrd.16072
Koichi Ushizawa, Toru Takahashi, Kanako Kaneyama, Tomoyuki Tokunaga, Yukio Tsunoda, Kazuyoshi Hashizume;
Gene expression profiles of bovine trophoblastic cell line (BT-1) analyzed by a custom cDNA microarray.
J. Reprod. Dev. 51:211-220(2005)

PubMed=16251743; DOI=10.1385/1-59259-983-4:177
Kazuyoshi Hashizume, Arata Shimada, Haruo Nakano, Toru Takahashi;
Bovine trophoblast cell culture systems: a technique to culture bovine trophoblast cells without feeder cells.
Methods Mol. Med. 121:179-188(2006)

PubMed=22632112; DOI=10.1186/1477-7827-10-41; PMCID=PMC3419082
Katsuo Koshi, Yasunori Suzuki, Yuki Nakaya, Kei Imai, Misa Hosoe, Toru Takahashi, Keiichiro Kizaki, Takayuki Miyazawa, Kazuyoshi Hashizume;
Bovine trophoblastic cell differentiation and binucleation involves enhanced endogenous retrovirus element expression.
Reprod. Biol. Endocrinol. 10:41.1-41.11(2012)

PubMed=24950590; DOI=10.1186/1477-7827-12-55; PMCID=PMC4078357
Mahmoud Awad, Katsuo Koshi, Keiichiro Kizaki, Toru Takahashi, Kazuyoshi Hashizume;
SOLD1 is expressed in bovine trophoblast cell lines and regulates cell invasiveness.
Reprod. Biol. Endocrinol. 12:55.1-55.10(2014)

Cross-references
Encyclopedic resources Wikidata; Q93432653
Entry history
Entry creation24-May-2019
Last entry update10-Apr-2025
Version number8