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Cellosaurus HOS-B55 (CVCL_WK80)

[Text version]
Cell line name HOS-B55
Accession CVCL_WK80
Resource Identification Initiative To cite this cell line use: HOS-B55 (RRID:CVCL_WK80)
Comments Population: Caucasian.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4932; HLA-B (Note=Allele B*55:02).
Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Bone, right femur; UBERON=UBERON_0000981.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg156Pro (c.467G>C); ClinVar=VCV000634768; Zygosity=Homozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0312 (HOS)
Sex of cell Female
Age at sampling 13Y
Category Cancer cell line
Publications

PubMed=15289353; DOI=10.1158/0008-5472.CAN-04-0522
Tomohide Tsukahara, Yuki Nabeta, Satoshi Kawaguchi, Hideyuki Ikeda, Yuriko Sato, Kumiko Shimozawa, Kazunori Ida, Hiroko Asanuma, Yoshihiko Hirohashi, Toshihiko Torigoe, Hiroaki Hiraga ...Show all 15 authors... , Satoshi Nagoya, Takuro Wada, Toshihiko Yamashita, Noriyuki Sato; Show fewer authors
Identification of human autologous cytotoxic T-lymphocyte-defined osteosarcoma gene that encodes a transcriptional regulator, papillomavirus binding factor.
Cancer Res. 64:5442-5448(2004)

Cross-references
Cell line databases/resources cancercelllines; CVCL_WK80
Encyclopedic resources Wikidata; Q94215802
Entry history
Entry creation24-May-2019
Last entry update14-Aug-2025
Version number12