Cellosaurus cell line PCK-CCL (CVCL

Cross-references
Cell line name	PCK-CCL
Accession	CVCL_WJ26
Resource Identification Initiative	To cite this cell line use: PCK-CCL (RRID:CVCL_WJ26)
Comments	Characteristics: Animal model of autosomal recessive polycystic kidney disease (PubMed=16783394). Doubling time: 28.8 hours (PubMed=16783394). Derived from site: In situ; Liver; UBERON=UBERON_0002107. Cell type: Cholangiocyte; CL=CL_1000488.
Sequence variations	Mutation; RGD; 1308476; Pkhd1; Unexplicit; IVS35-2A>T; Zygosity=Homozygous; Note=Splice acceptor mutation (PubMed=16783394).
Species of origin	Rattus norvegicus (Rat) (NCBI Taxonomy: 10116) Breed/subspecies: PCK/CrljCrl-Pkhd1pck/Crl; RS=RS_0001381.
Sex of cell	Sex unspecified
Age at sampling	2-3M
Category	Spontaneously immortalized cell line
Publications	PubMed=16783394; DOI=10.1038/labinvest.3700448 Melissa A. Muff, Tatyana V. Masyuk, Angela J. Stroope, Bing Q. Huang, Patrick L. Splinter, Seung-Ok Lee, Nicholas F. LaRusso; Development and characterization of a cholangiocyte cell line from the PCK rat, an animal model of autosomal recessive polycystic kidney disease. Lab. Invest. 86:940-950(2006)
Encyclopedic resources	Wikidata; Q98128523
Entry history
Entry creation	24-May-2019
Last entry update	10-Apr-2025
Version number	10