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Cellosaurus HCCLM3-GFP-LC3 (CVCL_WJ13)

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Cell line name HCCLM3-GFP-LC3
Accession CVCL_WJ13
Resource Identification Initiative To cite this cell line use: HCCLM3-GFP-LC3 (RRID:CVCL_WJ13)
Comments Group: Patented cell line.
Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C2010102.
Population: Chinese.
Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:6838; MAP1LC3A.
Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
Sequence variations
  • Mutation; HGNC; HGNC:14310; BRD7; Simple; p.Glu277Glyfs*18 (c.830_831delAG); Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:23177; KEAP1; Simple; p.Pro445Glnfs*13 (c.1334delC); Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu51Ter (c.151G>T); ClinVar=VCV000568781; Zygosity=Unspecified (from parent cell line).
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6832 (HCCLM3)
Sex of cell Male
Age at sampling 39Y
Category Cancer cell line
Publications

Patent=CN102115730A
Jia Fan, Ying-Hong Shi, Yuan-Fei Peng, Zhen-Bin Ding;
High metastatic potential hepatoma cell line capable of steady autophagy indication, and establishment method and application method thereof.
Patent number CN102115730A, 06-Jul-2011

PubMed=24058558; DOI=10.1371/journal.pone.0074407; PMCID=PMC3772859
Yuan-Fei Peng, Ying-Hong Shi, Ying-Hao Shen, Zhen-Bin Ding, Ai-Wu Ke, Jian Zhou, Shuang-Jian Qiu, Jia Fan;
Promoting colonization in metastatic HCC cells by modulation of autophagy.
PLoS ONE 8:e74407.1-e74407.12(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_WJ13
CCRID; 4201PAT-CCTCC00405
Encyclopedic resources Wikidata; Q93984342
Entry history
Entry creation24-May-2019
Last entry update10-Apr-2025
Version number11