Cellosaurus HELN(alpha) (CVCL_WI88)
| Cell line name | HELN(alpha) |
|---|---|
| Synonyms | HELN ERalpha; HELN-ERalpha |
| Accession | CVCL_WI88 |
| Resource Identification Initiative | To cite this cell line use: HELN(alpha) (RRID:CVCL_WI88) |
| Comments | Population: African American. Biotechnology: Used in a bioluminescent bioassay to quantitatively measure estrogenic compounds. Characteristics: The luciferase reporter gene is under the control of an estrogen-responsive element from the beta-globin promoter. Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:3467; ESR1. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002. |
| Disease | Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_WI87 (HELN) |
| Sex of cell | Female |
| Age at sampling | 30Y6M |
| Category | Cancer cell line |
| Publications | PubMed=10492897; DOI=10.1016/S0048-9697(99)00178-3 PubMed=11312541; DOI=10.1002/bio.630 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q94101425 |
| Entry history | |
| Entry creation | 24-May-2019 |
| Last entry update | 14-Aug-2025 |
| Version number | 13 |