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Cellosaurus NU (CVCL_WI75)

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Cell line name NU
Accession CVCL_WI75
Resource Identification Initiative To cite this cell line use: NU (RRID:CVCL_WI75)
Comments Population: Japanese.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu224Glu (c.672G>A); ClinVar=VCV000080709; Zygosity=Unspecified; Note=Splice site mutation (PubMed=1570156).
Disease Oral cavity squamous cell carcinoma (NCIt: C4833)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Publications

PubMed=1570156
Eiki Sakai, Nobuo Tsuchida;
Most human squamous cell carcinomas in the oral cavity contain mutated p53 tumor-suppressor genes.
Oncogene 7:927-933(1992)

PubMed=18097548; DOI=10.3892/ijo.32.1.101
Avaniyapuram Kannan Murugan, Nguyen Thi Hong, Yasuhisa Fukui, Arasambattu Kannan Munirajan, Nobuo Tsuchida;
Oncogenic mutations of the PIK3CA gene in head and neck squamous cell carcinomas.
Int. J. Oncol. 32:101-111(2008)

Cross-references
Cell line databases/resources cancercelllines; CVCL_WI75
Encyclopedic resources Wikidata; Q98128119
Polymorphism and mutation databases Cosmic; 1123032
Cosmic; 1123045
IARC_TP53; 1105
Entry history
Entry creation24-May-2019
Last entry update19-Dec-2024
Version number8