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Cellosaurus MOLM/AZA-1 (CVCL_WI20)

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Cell line name MOLM/AZA-1
Accession CVCL_WI20
Resource Identification Initiative To cite this cell line use: MOLM/AZA-1 (RRID:CVCL_WI20)
Comments Population: Japanese.
Doubling time: 17 hours (PubMed=28052028).
Selected for resistance to: ChEBI; CHEBI_2038; 5-azacytidine (5-azaC).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; HGNC:7132; KMT2A + HGNC; HGNC:7136; MLLT3; Name(s)=KMT2A-MLLT3, MLL-MLLT3, MLL-AF9 (from parent cell line).
  • Mutation; HGNC; HGNC:3765; FLT3; Unexplicit; Internal tandem duplication (FLT3-ITD); ClinVar=VCV000016270; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute monocytic leukemia (NCIt: C8263)
Myelodysplastic syndrome (NCIt: C3247)
Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2119 (MOLM-13)
Sex of cell Male
Age at sampling 20Y
Category Cancer cell line
Publications

PubMed=28052028; DOI=10.18632/oncotarget.14342; PMCID=PMC5355301
Eun-Hye Hur, Seung-Hyun Jung, Bon-Kwan Goo, Juhyun Moon, Yunsuk Choi, Dae Ro Choi, Yeun-Jun Chung, Je-Hwan Lee;
Establishment and characterization of hypomethylating agent-resistant cell lines, MOLM/AZA-1 and MOLM/DEC-5.
Oncotarget 8:11748-11762(2017)

Cross-references
Encyclopedic resources Wikidata; Q95990499
Entry history
Entry creation24-May-2019
Last entry update27-Nov-2025
Version number12