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Cellosaurus OUMS-24F/p53 (CVCL_WH83)

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Cell line name OUMS-24F/p53
Accession CVCL_WH83
Resource Identification Initiative To cite this cell line use: OUMS-24F/p53 (RRID:CVCL_WH83)
Comments Population: Japanese.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11998; TP53 (Note=With p.Arg273His).
Transformant: ChEBI; CHEBI_16907; 4-nitroquinoline N-oxide (4NQO).
Derived from site: In situ; Fetus; UBERON=UBERON_0000323.
Cell type: Fibroblast; CL=CL_0000057.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Heterozygous (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B370 (OUMS-24F)
Sex of cell Female
Age at sampling 6FW
Category Transformed cell line
Publications

DOI=10.11418/jtca1981.12.4_313
Masayoshi Namba, Li-Yan Bai, Yoshio Kano, Shigetaka Sugihara, Masahiro Miyazaki;
Multistep malignant transformation of human cells: immortalization of human fibroblasts by treatment with 60Co gamma rays and 4-nitroquinoline 1-oxide, and their malignant transformation with the ras oncogene.
Tissue Cult. Res. Commun. 12:313-318(1993)

PubMed=8148305
Masayoshi Namba, Mikio Iijima, Tadashi Kondo, Israt Jahan, Koichiro Mihara;
Immortalization of normal human cells is a multistep process and a rate limiting step of neoplastic transformation of the cells.
Hum. Cell 6:253-259(1993)

Cross-references
Encyclopedic resources Wikidata; Q98128397
Entry history
Entry creation24-May-2019
Last entry update19-Dec-2024
Version number10