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Cellosaurus 11-YX-1 (CVCL_WG97)

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Cell line name 11-YX-1
Accession CVCL_WG97
Resource Identification Initiative To cite this cell line use: 11-YX-1 (RRID:CVCL_WG97)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Population: Caucasian.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6563; LGALS3.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Sequence variations
  • Gene fusion; HGNC; HGNC:2092; CLTC + HGNC; HGNC:29559; VMP1; Name(s)=CLTC-VMP1 (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Val275fs*1 (c.821delG) (p.W274fs); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9884; RB1; Simple; c.265_607del343; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg249Ser (c.747G>C); ClinVar=VCV000406598; Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1092 (BT-549)
Sex of cell Female
Age at sampling 72Y
Category Cancer cell line
Publications

PubMed=21552935; DOI=10.3892/ijo.7.5.1079
Pratima Nangia-Makker, Erik Thompson, Chris Hogan, Josiah Ochieng, Avraham Raz;
Induction of tumorigenicity by galectin-3 in a nontumorigenic human breast-carcinoma cell-line.
Int. J. Oncol. 7:1079-1087(1995)

PubMed=9561029
Paula Rene Warfield, Pratima Nangia-Makker, Avraham Raz, Josiah Ochieng;
Adhesion of human breast carcinoma to extracellular matrix proteins is modulated by galectin-3.
Invasion Metastasis 17:101-112(1997)

Cross-references
Cell line databases/resources cancercelllines; CVCL_WG97
Encyclopedic resources Wikidata; Q93297249
Entry history
Entry creation24-May-2019
Last entry update27-Nov-2025
Version number13