Cell line name |
PER-278 |
Accession |
CVCL_W981 |
Resource Identification Initiative |
To cite this cell line use: PER-278 (RRID:CVCL_W981) |
Comments |
Doubling time: 62-68 hours (PubMed=2340491); 104 hours (PubMed=17117183). Omics: Transcriptomics; Microarray. Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371. |
Disease |
Childhood B acute lymphoblastic leukemia (NCIt: C9140) Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Sex of cell |
Male |
Age at sampling |
10Y |
Category |
Cancer cell line |
STR profile |
Source(s): PubMed=17117183
Markers:Amelogenin | X,Y |
CSF1PO | 11,12 |
D2S1338 | 23,25 |
D3S1358 | 18 |
D5S818 | 12,13 |
D7S820 | 11,12 |
D8S1179 | 11,12 |
D13S317 | 8,9 |
D16S539 | 13 |
D18S51 | 14,15 |
D19S433 | 13,15 |
D21S11 | 29,31 |
FGA | 24,27 |
TH01 | 6,8 |
TPOX | 8,11 |
vWA | 14,19 |
Run an STR similarity search on this cell line |
Publications | PubMed=2340491; DOI=10.1016/0165-4608(90)90105-J Kees U.R., Lukeis R.E., Ford J., Willoughby M.L.N., Garson O.M. Establishment and characterization of a childhood pre-B acute lymphoblastic leukemia cell line, PER-278, with chromosome translocations t(1;19) and t(1;9). Cancer Genet. Cytogenet. 46:201-208(1990) PubMed=7541097 Kees U.R., Ashman L.K. Synergistic action of interleukin-2 and Steel factor (SLF) on a human T lymphoblastoid cell line. Leukemia 9:1046-1050(1995) DOI=10.1016/B978-0-12-221970-2.50457-5 Drexler H.G. The leukemia-lymphoma cell line factsbook. (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001) PubMed=12883040 Kees U.R., Ford J., Watson M., Murch A.R., Ringner M., Walker R.L., Meltzer P.S. Gene expression profiles in a panel of childhood leukemia cell lines mirror critical features of the disease. Mol. Cancer Ther. 2:671-677(2003) PubMed=17117183; DOI=10.1038/sj.bjc.6603447; PMCID=PMC2360743 Beesley A.H., Palmer M.-L., Ford J., Weller R.E., Cummings A.J., Freitas J.R., Firth M.J., Perera K.U., de Klerk N.H., Kees U.R. Authenticity and drug resistance in a panel of acute lymphoblastic leukaemia cell lines. Br. J. Cancer 95:1537-1544(2006) |
Cross-references |
Encyclopedic resources |
Wikidata; Q54947180
|
Entry history |
Entry creation | 17-Jul-2014 |
Last entry update | 10-Apr-2025 |
Version number | 11 |
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