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Cellosaurus PER-278 (CVCL_W981)

[Text version]
Cell line name PER-278
Accession CVCL_W981
Resource Identification Initiative To cite this cell line use: PER-278 (RRID:CVCL_W981)
Comments Doubling time: 62-68 hours (PubMed=2340491); 104 hours (PubMed=17117183).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 10Y
Category Cancer cell line
STR profile Source(s): PubMed=17117183

Markers:
AmelogeninX,Y
CSF1PO11,12
D2S133823,25
D3S135818
D5S81812,13
D7S82011,12
D8S117911,12
D13S3178,9
D16S53913
D18S5114,15
D19S43313,15
D21S1129,31
FGA24,27
TH016,8
TPOX8,11
vWA14,19

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Publications

PubMed=2340491; DOI=10.1016/0165-4608(90)90105-J
Kees U.R., Lukeis R.E., Ford J., Willoughby M.L.N., Garson O.M.
Establishment and characterization of a childhood pre-B acute lymphoblastic leukemia cell line, PER-278, with chromosome translocations t(1;19) and t(1;9).
Cancer Genet. Cytogenet. 46:201-208(1990)

PubMed=7541097
Kees U.R., Ashman L.K.
Synergistic action of interleukin-2 and Steel factor (SLF) on a human T lymphoblastoid cell line.
Leukemia 9:1046-1050(1995)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=12883040
Kees U.R., Ford J., Watson M., Murch A.R., Ringner M., Walker R.L., Meltzer P.S.
Gene expression profiles in a panel of childhood leukemia cell lines mirror critical features of the disease.
Mol. Cancer Ther. 2:671-677(2003)

PubMed=17117183; DOI=10.1038/sj.bjc.6603447; PMCID=PMC2360743
Beesley A.H., Palmer M.-L., Ford J., Weller R.E., Cummings A.J., Freitas J.R., Firth M.J., Perera K.U., de Klerk N.H., Kees U.R.
Authenticity and drug resistance in a panel of acute lymphoblastic leukaemia cell lines.
Br. J. Cancer 95:1537-1544(2006)

Cross-references
Encyclopedic resources Wikidata; Q54947180
Entry history
Entry creation17-Jul-2014
Last entry update10-Apr-2025
Version number11