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Cellosaurus PER-255 (CVCL_W980)

[Text version]
Cell line name PER-255
Synonyms PER 255
Accession CVCL_W980
Resource Identification Initiative To cite this cell line use: PER-255 (RRID:CVCL_W980)
Comments Doubling time: 84-95 hours (PubMed=2546623); 66 hours (PubMed=17117183).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: T-cell; CL=CL_0000084.
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 5Y
Category Cancer cell line
STR profile Source(s): PubMed=17117183

Markers:
AmelogeninX,Y
CSF1PO10,11
D2S133817
D3S135815,18
D5S81812,13
D7S82011
D8S117914
D13S31712,13
D16S5399,12
D18S5119
D19S43313,14
D21S1130,31.2
FGA23,24
TH019,9.3
TPOX8
vWA16,17

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Publications

PubMed=2546623; DOI=10.1182/blood.V74.1.369.369
Ursula R. Kees, Robyn E. Lukeis, Jette Ford, Olga Margaret Garson;
Establishment and characterization of a childhood T-cell acute lymphoblastic leukemia cell line, PER-255, with chromosome abnormalities involving 7q32-34 in association with T-cell receptor-beta gene rearrangement.
Blood 74:369-373(1989)

PubMed=7541097
Ursula R. Kees, Leonie K. Ashman;
Synergistic action of interleukin-2 and Steel factor (SLF) on a human T lymphoblastoid cell line.
Leukemia 9:1046-1050(1995)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=12883040
Ursula R. Kees, Jette Ford, Marcia Watson, Ashleigh R. Murch, Markus Ringner, Robert L. Walker, Paul S. Meltzer;
Gene expression profiles in a panel of childhood leukemia cell lines mirror critical features of the disease.
Mol. Cancer Ther. 2:671-677(2003)

PubMed=17117183; DOI=10.1038/sj.bjc.6603447; PMCID=PMC2360743
Alex H. Beesley, Misty-Lee Palmer, Jette Ford, Richard E. Weller, Aaron J. Cummings, Joseph R. Freitas, Martin J. Firth, Kanchana U. Perera, Nick H. de Klerk, Ursula R. Kees;
Authenticity and drug resistance in a panel of acute lymphoblastic leukaemia cell lines.
Br. J. Cancer 95:1537-1544(2006)

Cross-references
Encyclopedic resources Wikidata; Q54947178
Entry history
Entry creation17-Jul-2014
Last entry update10-Apr-2025
Version number10