| Cell line name |
PER-255 |
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| Synonyms |
PER 255 |
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| Accession |
CVCL_W980 |
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| Resource Identification Initiative |
To cite this cell line use: PER-255 (RRID:CVCL_W980) |
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| Comments |
Doubling time: 84-95 hours (PubMed=2546623); 66 hours (PubMed=17117183).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: T-cell; CL=CL_0000084. |
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| Disease |
Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Sex of cell |
Male |
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| Age at sampling |
5Y |
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| Category |
Cancer cell line |
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| STR profile |
Source(s): PubMed=17117183
Markers:| Amelogenin | X,Y |
| CSF1PO | 10,11 |
| D2S1338 | 17 |
| D3S1358 | 15,18 |
| D5S818 | 12,13 |
| D7S820 | 11 |
| D8S1179 | 14 |
| D13S317 | 12,13 |
| D16S539 | 9,12 |
| D18S51 | 19 |
| D19S433 | 13,14 |
| D21S11 | 30,31.2 |
| FGA | 23,24 |
| TH01 | 9,9.3 |
| TPOX | 8 |
| vWA | 16,17 |
Run an STR similarity search on this cell line |
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| Publications | PubMed=2546623; DOI=10.1182/blood.V74.1.369.369
Kees U.R., Lukeis R., Ford J., Garson O.M.
Establishment and characterization of a childhood T-cell acute lymphoblastic leukemia cell line, PER-255, with chromosome abnormalities involving 7q32-34 in association with T-cell receptor-beta gene rearrangement.
Blood 74:369-373(1989) PubMed=7541097
Kees U.R., Ashman L.K.
Synergistic action of interleukin-2 and Steel factor (SLF) on a human T lymphoblastoid cell line.
Leukemia 9:1046-1050(1995) DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001) PubMed=12883040
Kees U.R., Ford J., Watson M., Murch A.R., Ringner M., Walker R.L., Meltzer P.S.
Gene expression profiles in a panel of childhood leukemia cell lines mirror critical features of the disease.
Mol. Cancer Ther. 2:671-677(2003) PubMed=17117183; DOI=10.1038/sj.bjc.6603447
Beesley A.H., Palmer M.-L., Ford J., Weller R.E., Cummings A.J., Freitas J.R., Firth M.J., Perera K.U., de Klerk N.H., Kees U.R.
Authenticity and drug resistance in a panel of acute lymphoblastic leukaemia cell lines.
Br. J. Cancer 95:1537-1544(2006) |
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| Cross-references |
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| Encyclopedic resources |
Wikidata; Q54947178
|
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| Entry history |
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| Entry creation | 17-Jul-2014 |
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| Last entry update | 29-Jun-2023 |
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| Version number | 9 |
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