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Cellosaurus PER-117 (CVCL_W979)

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Cell line name PER-117
Synonyms PER 117
Accession CVCL_W979
Resource Identification Initiative To cite this cell line use: PER-117 (RRID:CVCL_W979)
Comments Doubling time: 55-65 hours (PubMed=3472019); 56 hours (PubMed=17117183).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: T-cell; CL=CL_0000084.
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 2Y
Category Cancer cell line
STR profile Source(s): PubMed=17117183

Markers:
AmelogeninX,Y
CSF1PO10,13
D2S133816,17
D3S135815,17
D5S81811,12
D7S8209,13
D8S117913
D13S3178,11,12
D16S53911,13
D18S5112,13
D19S43314
D21S1131,32.2
FGA23,24
TH018,9.3
TPOX8,11
vWA14,17

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Publications

PubMed=3472019; DOI=10.1016/0145-2126(87)90082-8
Ursula R. Kees, Jette Ford, P. James Price, Brian F. Meyer, Richard P. Herrmann;
PER-117: a new human ALL cell line with an immature thymic phenotype.
Leuk. Res. 11:489-498(1987)

PubMed=7541097
Ursula R. Kees, Leonie K. Ashman;
Synergistic action of interleukin-2 and Steel factor (SLF) on a human T lymphoblastoid cell line.
Leukemia 9:1046-1050(1995)

PubMed=10556553; DOI=10.1016/S0022-1759(99)00088-5
Viatcheslav A. Mordvinov, Susanne E. Peroni, Monica L. De Boer, Ursula R. Kees, Colin John Sanderson;
A human T-cell line with inducible production of interleukins 5 and 4. A model for studies of gene expression.
J. Immunol. Methods 228:163-168(1999)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=12883040
Ursula R. Kees, Jette Ford, Marcia Watson, Ashleigh R. Murch, Markus Ringner, Robert L. Walker, Paul S. Meltzer;
Gene expression profiles in a panel of childhood leukemia cell lines mirror critical features of the disease.
Mol. Cancer Ther. 2:671-677(2003)

PubMed=17117183; DOI=10.1038/sj.bjc.6603447; PMCID=PMC2360743
Alex H. Beesley, Misty-Lee Palmer, Jette Ford, Richard E. Weller, Aaron J. Cummings, Joseph R. Freitas, Martin J. Firth, Kanchana U. Perera, Nick H. de Klerk, Ursula R. Kees;
Authenticity and drug resistance in a panel of acute lymphoblastic leukaemia cell lines.
Br. J. Cancer 95:1537-1544(2006)

Cross-references
Encyclopedic resources Wikidata; Q54947174
Entry history
Entry creation17-Jul-2014
Last entry update10-Apr-2025
Version number11