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Cellosaurus PER-145 (CVCL_W976)

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Cell line name PER-145
Accession CVCL_W976
Resource Identification Initiative To cite this cell line use: PER-145 (RRID:CVCL_W976)
Comments Doubling time: 108 hours (PubMed=17117183).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_W977 ! PER-163
CVCL_W978 ! PER-164
Sex of cell Male
Age at sampling 19Y
Category Cancer cell line
STR profile Source(s): PubMed=17117183

Markers:
AmelogeninX,Y
CSF1PO11,13
D2S133816,19
D3S135818
D5S81810,11
D7S82010,12
D8S11799,11
D13S3178,9
D16S53912,13
D18S5114,16
D19S43316
D21S1130,33.2
FGA19,20
TH016,9.3
TPOX9,11
vWA17

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Publications

PubMed=3472651
Ursula R. Kees;
Resistance to 1-beta-D-arabinofuranosylcytosine after high-dose treatment childhood lymphoblastic leukemia: isolation of a drug resistant and a sensitive cell line.
Cancer Res. 47:3088-3091(1987)

PubMed=2720661
Ursula R. Kees, Jette Ford, Vaille M. Dawson, Evelyn M. Piall, G. Wynne Aherne;
Development of resistance to 1-beta-D-arabinofuranosylcytosine after high-dose treatment in childhood lymphoblastic leukemia: analysis of resistance mechanism in established cell lines.
Cancer Res. 49:3015-3019(1989)

PubMed=7540895; DOI=10.1097/00001813-199504000-00015
Ursula R. Kees, Vassilios I. Avramis;
Biochemical pharmacology and DNA methylation studies of arabinosyl 5-azacytidine and 5,6-dihydro-5-azacytidine in two human leukemia cell lines PER-145 and PER-163.
Anticancer Drugs 6:303-310(1995)

PubMed=7541097
Ursula R. Kees, Leonie K. Ashman;
Synergistic action of interleukin-2 and Steel factor (SLF) on a human T lymphoblastoid cell line.
Leukemia 9:1046-1050(1995)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=12883040
Ursula R. Kees, Jette Ford, Marcia Watson, Ashleigh R. Murch, Markus Ringner, Robert L. Walker, Paul S. Meltzer;
Gene expression profiles in a panel of childhood leukemia cell lines mirror critical features of the disease.
Mol. Cancer Ther. 2:671-677(2003)

PubMed=17117183; DOI=10.1038/sj.bjc.6603447; PMCID=PMC2360743
Alex H. Beesley, Misty-Lee Palmer, Jette Ford, Richard E. Weller, Aaron J. Cummings, Joseph R. Freitas, Martin J. Firth, Kanchana U. Perera, Nick H. de Klerk, Ursula R. Kees;
Authenticity and drug resistance in a panel of acute lymphoblastic leukaemia cell lines.
Br. J. Cancer 95:1537-1544(2006)

Cross-references
Encyclopedic resources Wikidata; Q54947175
Entry history
Entry creation17-Jul-2014
Last entry update10-Apr-2025
Version number10