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Cellosaurus CTN3 (CVCL_W952)

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Cell line name CTN3
Accession CVCL_W952
Resource Identification Initiative To cite this cell line use: CTN3 (RRID:CVCL_W952)
Comments Knockout cell: Method=KO mouse; MGI; MGI:97874; Rb1 (Note=1 of 2 alleles).
Genetic integration: Method=Transgenic mouse; Gene=HGNC; HGNC:9884; RB1.
Disease Mouse medullary thyroid carcinoma (NCIt: C24170)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: Rb+/- Tg(POMC-RB)109Ayn.
Sex of cell Male
Age at sampling 1Y1M
Category Cancer cell line
Publications

PubMed=15705875
Zong-Xiang Zhou, Andrea Flesken-Nikitin, Corinna Gehrett Levine, Elena N. Shmidt, Jessica P. Eng, Ekaterina Y. Nikitina, David M. Spencer, Alexander Y. Nikitin;
Suppression of melanotroph carcinogenesis leads to accelerated progression of pituitary anterior lobe tumors and medullary thyroid carcinomas in Rb+/- mice.
Cancer Res. 65:787-796(2005)

PubMed=17893233; DOI=10.1093/carcin/bgm207
Andres Matoso, Zong-Xiang Zhou, Ryo Hayama, Andrea Flesken-Nikitin, Alexander Y. Nikitin;
Cell lineage-specific interactions between Men1 and Rb in neuroendocrine neoplasia.
Carcinogenesis 29:620-628(2008)

PubMed=22538498; DOI=10.1159/000338793
Simona Grozinsky-Glasberg, Ilan Shimon, Hadara Rubinfeld;
The role of cell lines in the study of neuroendocrine tumors.
Neuroendocrinology 96:173-187(2012)

Cross-references
Encyclopedic resources Wikidata; Q54814763
Entry history
Entry creation17-Jul-2014
Last entry update19-Dec-2024
Version number7