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Cellosaurus Beta-TC-1 (CVCL_W951)

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Cell line name Beta-TC-1
Synonyms beta TC1; BetaTC1
Accession CVCL_W951
Resource Identification Initiative To cite this cell line use: Beta-TC-1 (RRID:CVCL_W951)
Comments Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
Cell type: Pancreatic beta cell; CL=CL_0000169.
Disease Mouse insulinoma (NCIt: C34053)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: (C57BL/6J x DBA/2J)F2 transgenic RIPTag4.
Category Transformed cell line
Publications

PubMed=2848253; DOI=10.1073/pnas.85.23.9037; PMCID=PMC282658
Shimon Efrat, Susanne Linde, Hans Kofod, David L. Spector, Michael Delannoy, Seth Garran Niels Grant, Douglas Hanahan, Steinunn Baekkeskov;
Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene.
Proc. Natl. Acad. Sci. U.S.A. 85:9037-9041(1988)

Cross-references
Encyclopedic resources Wikidata; Q54796092
Entry history
Entry creation17-Jul-2014
Last entry update14-Aug-2025
Version number8