• Gene fusion; HGNC; 1097; BRAF + HGNC; 7112; MKRN1; Name(s)=MKRN1-BRAF; Note=In frame (PubMed=26680454; PubMed=30737244).
  
• Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (PubMed=23833040; PubMed=26680454; PubMed=30737244).
  
• Mutation; HGNC; 3373; EP300; Simple; p.Ser799Phefs*5 (c.2396delC); Zygosity=Homozygous (PubMed=26680454; PubMed=30737244).
  
• Mutation; HGNC; 9967; RET; Simple; p.Glu90Lys (c.268G>A); Zygosity=Heterozygous (PubMed=26680454; PubMed=30737244).
  
• Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Heterozygous; Note=In promoter (PubMed=23833040; PubMed=30737244).
  
• Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (PubMed=30737244).
  

PubMed=20810568; DOI=10.1210/jc.2010-1421
Marlow L.A., D'Innocenzi J., Zhang Y.-L., Rohl S.D., Cooper S.J., Sebo T.J., Grant C., McIver B., Kasperbauer J.L., Wadsworth J.T., Casler J.D., Kennedy P.W., Highsmith W.E. Jr., Clark O., Milosevic D., Netzel B.C., Cradic K.W., Arora S., Beaudry C., Grebe S.K.G., Silverberg M.L., Azorsa D.O., Smallridge R.C., Copland J.A. III
Detailed molecular fingerprinting of four new anaplastic thyroid carcinoma cell lines and their use for verification of RhoB as a molecular therapeutic target.
J. Clin. Endocrinol. Metab. 95:5338-5347(2010)

PubMed=23724124; DOI=10.1371/journal.pone.0065095
Li W., Reeb A.N., Sewell W.A., Elhomsy G., Lin R.-Y.
Phenotypic characterization of metastatic anaplastic thyroid cancer stem cells.
PLoS ONE 8:E65095-E65095(2013)

PubMed=23833040; DOI=10.1210/jc.2013-2383
Landa I., Ganly I., Chan T.A., Mitsutake N., Matsuse M., Ibrahimpasic T., Ghossein R.A., Fagin J.A.
Frequent somatic TERT promoter mutations in thyroid cancer: higher prevalence in advanced forms of the disease.
J. Clin. Endocrinol. Metab. 98:E1562-E1566(2013)

PubMed=25675381; DOI=10.1210/jc.2014-2764
von Roemeling C.A., Marlow L.A., Pinkerton A.B., Crist A., Miller J., Tun H.W., Smallridge R.C., Copland J.A. III
Aberrant lipid metabolism in anaplastic thyroid carcinoma reveals stearoyl CoA desaturase 1 as a novel therapeutic target.
J. Clin. Endocrinol. Metab. 100:E697-E709(2015)

PubMed=26680454; DOI=10.1186/s12885-015-1955-9
Kasaian K., Wiseman S.M., Walker B.A., Schein J.E., Zhao Y.-J., Hirst M., Moore R.A., Mungall A.J., Marra M.A., Jones S.J.M.
The genomic and transcriptomic landscape of anaplastic thyroid cancer: implications for therapy.
BMC Cancer 15:984.1-984.11(2015)

PubMed=30737244; DOI=10.1158/1078-0432.CCR-18-2953
Landa I., Pozdeyev N., Korch C.T., Marlow L.A., Smallridge R.C., Copland J.A. III, Henderson Y.C., Lai S.Y., Clayman G.L., Onoda N., Tan A.-C., Garcia-Rendueles M.E.R., Knauf J.A., Haugen B.R., Fagin J.A., Schweppe R.E.
Comprehensive genetic characterization of human thyroid cancer cell lines: a validated panel for preclinical studies.
Clin. Cancer Res. 25:3141-3151(2019)