Cellosaurus cell line OANC1 (CVCL

Cellosaurus OANC1 (CVCL_W891)

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Cell line name

OANC1

Accession

CVCL_W891

Resource Identification Initiative

To cite this cell line use: OANC1 (RRID:CVCL_W891)

Comments

Doubling time: ~48 hours (PubMed=24077944).
Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.

Sequence variations

Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Arg445Ter (c.1333C>T); ClinVar=VCV000024850; Zygosity=Homozygous (PubMed=24077944).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu286Lys (c.856G>A); ClinVar=VCV000183752; Zygosity=Homozygous (PubMed=24077944).

Disease

Barrett adenocarcinoma (NCIt: C7027)
Adenocarcinoma of the esophagus (ORDO: Orphanet_99976)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

44Y

Category

Cancer cell line

STR profile

Source(s): PubMed=24077944

Markers:

Amelogenin	X
CSF1PO	9
D3S1358	15
D5S818	13
D7S820	10,12
D8S1179	15
D13S317	8
D16S539	13
D18S51	19
D21S11	31
FGA	22
Penta D	11
Penta E	7,10
TH01	7
TPOX	8,12
vWA	18

Publications

PubMed=24077944; DOI=10.1007/s10620-013-2882-8
Nicholas J. Clemons, Hong-Do Do, Christina Fennell, Siddhartha Deb, Andrew Fellowes, Alexander Dobrovic, Wayne A. Phillips;
Characterization of a novel tumorigenic esophageal adenocarcinoma cell line: OANC1.
Dig. Dis. Sci. 59:78-88(2014)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_W891

Encyclopedic resources

Wikidata; Q54931680

Polymorphism and mutation databases

Cosmic; 2030752

Entry history

Entry creation

17-Jul-2014

Last entry update

19-Dec-2024

Version number