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Cellosaurus BRG-M (CVCL_W882)

[Text version]
Cell line name BRG-M
Synonyms BRG M; BRG IgM; BRG-IgM; BRG-P.1
Accession CVCL_W882
Resource Identification Initiative To cite this cell line use: BRG-M (RRID:CVCL_W882)
Comments Population: Caucasian.
Characteristics: IgM producing subclone of BRG-P.
Virology: EBV-negative.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg158His (c.473G>A); ClinVar=VCV000141963; Zygosity=Heterozygous (PubMed=9399658).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu286Gly (c.857_858AA>GT); Zygosity=Heterozygous (PubMed=9399658).
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_W880 (BRG-P)
Children:
CVCL_UI47 (BRG-H)
Sex of cell Female
Age at sampling 30Y
Category Cancer cell line
Publications

PubMed=8207254; DOI=10.4049/jimmunol.153.1.45
Rita Jain, Silvio Roncella, Shiori Hashimoto, Anna Carbone, Paolo Francia di Celle, Robin Foa, Manlio Ferrarini, Nicholas Chiorazzi;
A potential role for antigen selection in the clonal evolution of Burkitt's lymphoma.
J. Immunol. 153:45-52(1994)

PubMed=8695808; DOI=10.1182/blood.V88.2.599.bloodjournal882599
Silvio Roncella, Giovanna Cutrona, Anna Favre, Massimo Ulivi, Franco Fais, Alessandra Signorini, Carlo E. Grossi, Nicholas Chiorazzi, Manlio Ferrarini;
Apoptosis of Burkitt's lymphoma cells induced by specific interaction of surface IgM with a self-antigen: implications for lymphomagenesis in acquired immunodeficiency syndrome.
Blood 88:599-608(1996)

PubMed=9399658; DOI=10.1002/(SICI)1097-0215(19971210)73:6<816::AID-IJC8>3.0.CO;2-5
Paola Campomenosi, Gilberto Fronza, Laura Ottaggio, Silvio Roncella, Alberto Inga, Massimo Bogliolo, Paola Monti, Paola Assereto, Francesca Moro, Giovanna Cutrona, Simonetta Bozzo, Nicholas Chiorazzi, Angelo Abbondandolo ...Show all 14 authors... , Manlio Ferrarini; Show fewer authors
Heterogeneous p53 mutations in a Burkitt lymphoma from an AIDS patient with monoclonal c-myc and VDJ rearrangements.
Int. J. Cancer 73:816-821(1997)

PubMed=10702812
Annalisa Zunino, Silvia Viaggi, Laura Ottaggio, Gilberto Fronza, Andrea Schenone, Silvio Roncella, Angelo Abbondandolo;
Chromosomal aberrations evaluated by CGH, FISH and GTG-banding in a case of AIDS-related Burkitt's lymphoma.
Haematologica 85:250-255(2000)

Cross-references
Cell line databases/resources cancercelllines; CVCL_W882
Encyclopedic resources Wikidata; Q54798229
Polymorphism and mutation databases Cosmic; 1515196
IARC_TP53; 6585
Entry history
Entry creation17-Jul-2014
Last entry update19-Dec-2024
Version number14