Cellosaurus cell line BRG-A (CVCL

Cellosaurus BRG-A (CVCL_W881)

Cross-references
Cell line name	BRG-A
Synonyms	BRG A; BRG IgA; BRG-IgA; BRGIgA; BrgIgA; BRG-P.5
Accession	CVCL_W881
Resource Identification Initiative	To cite this cell line use: BRG-A (RRID:CVCL_W881)
Comments	Population: Caucasian. Characteristics: IgA1 producing subclone of BRG-P. Virology: EBV-negative. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. Cell type: B-cell; CL=CL_0000236.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln354Glu (c.1060C>G); ClinVar=VCV001061283; Zygosity=Hemizygous (PubMed=9399658).
Disease	Burkitt lymphoma (NCIt: C2912) Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_W880 (BRG-P)
Sex of cell	Female
Age at sampling	30Y
Category	Cancer cell line
Publications	PubMed=8207254; DOI=10.4049/jimmunol.153.1.45 Rita Jain, Silvio Roncella, Shiori Hashimoto, Anna Carbone, Paolo Francia di Celle, Robin Foa, Manlio Ferrarini, Nicholas Chiorazzi; A potential role for antigen selection in the clonal evolution of Burkitt's lymphoma. J. Immunol. 153:45-52(1994) PubMed=9399658; DOI=10.1002/(SICI)1097-0215(19971210)73:6<816::AID-IJC8>3.0.CO;2-5 Paola Campomenosi, Gilberto Fronza, Laura Ottaggio, Silvio Roncella, Alberto Inga, Massimo Bogliolo, Paola Monti, Paola Assereto, Francesca Moro, Giovanna Cutrona, Simonetta Bozzo, Nicholas Chiorazzi, Angelo Abbondandolo ...Show all 14 authors... , Manlio Ferrarini; Show fewer authors Heterogeneous p53 mutations in a Burkitt lymphoma from an AIDS patient with monoclonal c-myc and VDJ rearrangements. Int. J. Cancer 73:816-821(1997) PubMed=10702812 Annalisa Zunino, Silvia Viaggi, Laura Ottaggio, Gilberto Fronza, Andrea Schenone, Silvio Roncella, Angelo Abbondandolo; Chromosomal aberrations evaluated by CGH, FISH and GTG-banding in a case of AIDS-related Burkitt's lymphoma. Haematologica 85:250-255(2000)
Cell line databases/resources	cancercelllines; CVCL_W881
Encyclopedic resources	Wikidata; Q54798227
Polymorphism and mutation databases	Cosmic; 1515197 IARC_TP53; 6587
Entry history
Entry creation	17-Jul-2014
Last entry update	19-Dec-2024
Version number	14